Female infertility due to zona pellucida defect
MONDO:0014342Female infertility due to zona pellucida defect is a rare, genetic, female infertility disorder characterized by the presence of abnormal oocytes that lack a zona pellucida. Affected individuals are unable to conceive despite having normal menstrual cycles and sex hormone levels, as well as no obstructions in the fallopian tubes or defects of the uterus or adnexa.
Also known as: OOMD, OOMD1, oocyte maturation defect, oocyte maturation defect 1
69 clinical trials for this condition and its sub-types.
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New IVF drug trial halted early: did it help embryo growth?
Disease control TerminatedThis early-stage trial tested whether adding the drug FE999302 to standard IVF hormones could increase the number of high-quality embryos in women undergoing fertility treatment. The study enrolled 310 women aged 18–40 with specific hormone levels. The trial was terminated early,…
Phase: PHASE1 • Sponsor: Ferring Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Timing of fertility drug may affect egg quality in IVF
Disease control TerminatedThis early-phase study looked at whether giving an extra fertility drug (FE 999302) at different times during ovarian stimulation could improve the number of good-quality embryos in women undergoing IVF. The trial included 106 women with high ovarian reserve and was stopped early…
Phase: PHASE1 • Sponsor: Ferring Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Does Dad's smoking harm fertility? new study investigates
Knowledge-focused TerminatedThis study looked at how a man's smoking habits might affect a couple's ability to have a baby. Researchers compared fertile and infertile couples, measuring smoking markers like carbon monoxide and cotinine in blood, semen, and hair. The goal was to understand if smoking damages…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC