Familial juvenile hypertrophy of the breast
MONDO:0007237Familial juvenile hypertrophy of the breast is a rare breast malformation disorder characterized by unilateral or bilateral, symmetrical or asymmetrical, uncontrolled, rapid and massive enlargement of the breast(s) in peripubertal females, occurring in various members of a family. Additional associated manifestations may include skin hyperemia, dilated subcutaneous veins, skin necrosis, kyphosis, lordosis and anonychia. Growth and development are otherwise normal.
Also known as: familial juvenile gigantomastia, juvenile gigantomastia, juvenile macromastia, virginal breast hypertrophy, virginal mammary hypertrophy, JHB, gigantomastia, juvenile, hypertrophy of the breast, juvenile
7 clinical trials for this condition and its sub-types.
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Could a safer, No-Needle MRI replace Dye-Based breast scans?
Diagnosis OngoingThis study is testing whether a special MRI that does not require a contrast dye injection can accurately detect breast cancer or other breast diseases. Over 1,000 women at risk or with suspected breast issues will receive the new MRI alongside standard care. The goal is to see i…
Sponsor: Perspectum • Aim: Diagnosis
Last updated Jun 27, 2026 12:36 UTC
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New pain drug could ease recovery after breast surgery
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether a painkiller called suzetrigine can reduce pain after breast surgery (not mastectomy). About 120 adults will take the drug along with a nerve block. Their pain levels will be compared to past patients who had standard care. The goal is to see if this comb…
Phase: PHASE4 • Sponsor: University of California, San Diego • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC