Epithelioid sarcoma
MONDO:0017387An aggressive malignant neoplasm of uncertain differentiation, characterized by the presence of epithelioid cells forming nodular patterns. The nodules often undergo central necrosis, resulting in a pseudogranulomatous growth pattern. It usually occurs in young adults. The most common sites of involvement are the extremities (distal-type epithelioid sarcoma), and less frequently the pelvis, perineum, and genital organs (proximal-type epithelioid sarcoma).
Also known as: ES, epithelioid cell sarcoma, epithelioid sarcoma
2836 clinical trials for this condition and its sub-types, 20 tagged with Epithelioid sarcoma itself.
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Sub-types of Epithelioid sarcoma
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Adult epithelioid sarcoma 0 trials
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Childhood epithelioid sarcoma 0 trials
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Peripheral epithelioid sarcoma 0 trials
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Proximal-type epithelioid sarcoma 0 trials
1 sub-type
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Experimental combo for rare sarcoma shows early promise but trial halted
Disease control Stopped earlyThis study tested a new drug called tazemetostat combined with standard chemotherapy (doxorubicin) in people with advanced epithelioid sarcoma, a rare soft-tissue cancer. The trial aimed to find a safe dose and see if the combination could help patients live longer without their …
Phase 1 • Sponsor: Epizyme, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Experimental cancer drug LY3405105 fails to advance in early trial
Disease control Stopped earlyThis early-phase study tested the safety of an oral drug called LY3405105 in 54 people with advanced solid tumors. The trial was divided into two parts to find the right dose and to see if the drug could shrink tumors. However, the study was terminated early, meaning the drug did…
Phase 1 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC