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Ectopic Cushing syndrome

MONDO:0020527

A form of ACTH-dependent Cushing syndrome caused by excess secretion of ACTH by a benign or, more often, malignant non-pituitary tumor.

Also known as: Cushing syndrome due to ectopic ACTH secretion, adrenocorticotropic hormone secretion syndrome, ectopic ACTH secreting tumor, ectopic ACTH secreting tumour, ectopic Cushing syndrome, occult ectopic ACTH secretion, paraneoplastic Cushing syndrome

6 clinical trials for this condition and its sub-types.

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Broader categories

Disease (680) Nervous system disorder (231) Brain disorder (125) Central nervous system disorder (107) Endocrine system disorder (72) Cushing syndrome (41) Syndromic disease (25) ACTH-dependent Cushing syndrome (22) Pituitary gland disorder (16) Reproductive system disorder (15)
Trials to join now! 3 Not yet recruiting 1 Not yet finished but already full! 1 Completed 1
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  • New drug shows promise for cortisol disorder

    Disease control Completed

    This study tested an experimental drug called SPI-62 in 26 adults with Cushing's syndrome caused by a non-adrenal tumor. The goal was to see if SPI-62 could lower cortisol levels safely. Participants received either SPI-62 or a placebo for 24 weeks, with an option to continue lon…

    Phase: PHASE2 • Sponsor: Sparrow Pharmaceuticals • Aim: Disease control

    Last updated Jun 27, 2026 07:53 UTC

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