Coronary stenosis

This registry will follow 2000 people with complex coronary artery disease who receive the Inspiron EVO drug-eluting stent. The stent is designed to be easier to deliver and stronger than standard stents. Researchers will track how well the stent works and whether it reduces hear…

This study tests a new laser system designed to vaporize plaque in blocked coronary arteries before doctors place a stent. The trial compares the new laser device to an existing one in about 218 people with severe heart artery narrowing. The main goal is to see if the new system …

This study compares a drug-coated balloon (DCB) to a drug-eluting stent (DES) for treating new blockages in heart arteries. About 1,548 adults with stable or unstable angina, old heart attacks, or silent ischemia will be randomly assigned to one of the two treatments. The main go…

This study tests if using a drug-coated balloon along with a stent works better than a stent alone for people with complex blockages in the left main coronary artery. About 186 adults with this condition will be randomly assigned to one of two treatments. The goal is to see which…

This study tests whether a simple, 1-minute electrocardiogram (ECG) analyzed by artificial intelligence can accurately detect significant blockages in the heart's arteries. Researchers will compare the AI's predictions against standard imaging tests in 400 adults. If successful, …

This study aims to understand why some people's coronary artery disease gets worse quickly while others' stays stable. Researchers will compare medical history, lab results, and imaging from 52 patients—34 with rapidly progressive disease and 18 with non-rapidly progressive disea…

This study tests whether using very low radiation doses combined with special software can produce clear images of the heart's arteries. About 50 adults scheduled for a standard heart angiogram will have extra images taken with the new low-radiation method. The goal is to see if …