Corneal dystrophy
MONDO:0018102The term corneal dystrophy embraces a heterogeneous group of bilateral genetically determined non-inflammatory corneal diseases that are usually restricted to the cornea. The designation is imprecise but remains in vogue because of its clinical value.
Also known as: corneal dystrophy, corneal dystrophy (disease)
66 clinical trials for this condition and its sub-types, 6 tagged with Corneal dystrophy itself.
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Sub-types of Corneal dystrophy
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Corneal endothelial dystrophy 5 trials · 36 incl. sub-types
4 sub-types
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Posterior corneal dystrophy 0 trials · 34 incl. sub-types
6 sub-types
- Fuchs' endothelial dystrophy 33 trials Sub-types →
- Congenital hereditary endothelial dystrophy of cornea 2 trials
- Posterior polymorphous corneal dystrophy 1 trial Sub-types →
- X-linked endothelial corneal dystrophy 0 trials
- Central cloudy dystrophy of François 0 trials
- Congenital hereditary endothelial dystrophy type I 0 trials
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Stromal corneal dystrophy 2 trials · 16 incl. sub-types
10 sub-types
- Macular corneal dystrophy 13 trials
- Fleck corneal dystrophy 1 trial
- Schnyder corneal dystrophy 0 trials
- Central cloudy dystrophy of François 0 trials
- Congenital stromal corneal dystrophy 0 trials
- Granular corneal dystrophy type I 0 trials
- Granular corneal dystrophy type II 0 trials
- Lattice corneal dystrophy 0 trials Sub-types →
- Posterior amorphous corneal dystrophy 0 trials
- Pre-descemet corneal dystrophy 0 trials
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Superficial corneal dystrophy 0 trials · 7 incl. sub-types
12 sub-types
- Corneal intraepithelial dyskeratosis-palmoplantar hyperkeratosis-laryngeal dyskeratosis syndrome 4 trials
- Epithelial basement membrane dystrophy 2 trials
- Thiel-Behnke corneal dystrophy 1 trial
- Grayson-Wilbrandt corneal dystrophy 0 trials
- Lisch epithelial corneal dystrophy 0 trials
- Meesmann corneal dystrophy 0 trials Sub-types →
- Reis-Bucklers corneal dystrophy 0 trials
- Epithelial recurrent erosion dystrophy 0 trials
- Gelatinous drop-like corneal dystrophy 0 trials
- Hereditary benign intraepithelial dyskeratosis 0 trials
- Honey-droplet corneal dystrophy 0 trials
- Subepithelial mucinous corneal dystrophy 0 trials
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Epithelial-stromal TGFBI dystrophy 1 trial · 3 incl. sub-types
8 sub-types
- Epithelial basement membrane dystrophy 2 trials
- Thiel-Behnke corneal dystrophy 1 trial
- Reis-Bucklers corneal dystrophy 0 trials
- Corneal dystrophy, lattice type 3A 0 trials
- Corneal granular dystrophy 0 trials
- Granular corneal dystrophy type I 0 trials
- Granular corneal dystrophy type II 0 trials
- Lattice corneal dystrophy type I 0 trials
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Chandler syndrome 2 trials
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Epithelial and subepithelial corneal dystrophy 0 trials · 2 incl. sub-types
5 sub-types
- Epithelial basement membrane dystrophy 2 trials
- Lisch epithelial corneal dystrophy 0 trials
- Meesmann corneal dystrophy 0 trials Sub-types →
- Gelatinous drop-like corneal dystrophy 0 trials
- Subepithelial mucinous corneal dystrophy 0 trials
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Finnish type amyloidosis 0 trials
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Judge Misch wright syndrome 0 trials
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Autosomal dominant keratitis 0 trials
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Band keratopathy 0 trials
Most studied deeper sub-types
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New eye scanner could sharpen diagnosis of corneal problems
Diagnosis Recruiting nowThis study aims to improve how doctors detect, classify, and treat irregular corneas caused by conditions like keratoconus, dry eye, and corneal scars. Researchers will use a special imaging device called optical coherence tomography (OCT) to get detailed measurements of the corn…
Sponsor: Oregon Health and Science University • Aim: Diagnosis
Last updated Jun 26, 2026 14:49 UTC
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Massive eye gene bank aims to unlock secrets of rare blindness
Knowledge-focused Recruiting nowThis study aims to collect DNA samples and detailed eye exam data from 1,000 people with rare inherited eye diseases like aniridia, Best disease, and albinism. Participants provide a saliva or blood sample and share their eye health records. The goal is to expand a research repos…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Gene study aims to unlock secrets of common corneal disease
Knowledge-focused Recruiting nowThis study is looking at how genes relate to the different forms of Fuchs corneal endothelial dystrophy, a common eye disease that affects the cornea. Researchers in France will enroll 500 people who need corneal transplant surgery. They will analyze blood samples for genetic mar…
Sponsor: Centre Hospitalier Universitaire de Saint Etienne • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Super-Scope for eyes: imaging trial spots hidden clues in blindness
Knowledge-focused Recruiting nowThis study tests a high-resolution imaging system to see tiny structures in the eye that routine tools cannot detect. Researchers will scan 1,200 people with various eye conditions and healthy volunteers. The goal is to better understand diseases like glaucoma, diabetes, and reti…
Sponsor: Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC