Cornea plana
MONDO:0000733A rare developmental defect of the eye characterized by usually bilateral absence of the normal protrusion of the cornea from the sclera, the corneal curvature being the same as that of the adjacent sclera. Most patients develop hyperopia, hazy corneal limbus, and arcus lipoides at an early age. The condition may present as an autosomal dominant or an autosomal recessive form, with the latter showing more severe signs and symptoms (such as a round and opaque thickening located centrally in the cornea) and more frequent association with other ocular anomalies.
Also known as: congenital cornea plana, flat cornea
17 clinical trials for this condition and its sub-types.
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Broader categories
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Laser before eye implant may prevent glaucoma damage
Disease control Recruiting nowThis study tests whether giving a laser treatment (transscleral cyclophotocoagulation) to lower eye pressure before a Boston keratoprosthesis (a plastic cornea implant) can prevent or slow glaucoma. Twenty adults who need the implant will receive one of two laser types 4-8 weeks …
Phase: NA • Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New eye scanner could sharpen diagnosis of glaucoma and retina diseases
Diagnosis Recruiting nowThis study is testing a new eye imaging device called the VG200D, which uses advanced technology to take detailed pictures of the eye. Researchers want to see if it works as well as a standard device for measuring parts of the eye in people with glaucoma, retina problems, corneal…
Sponsor: Intalight, Inc • Aim: Diagnosis
Last updated Jun 27, 2026 08:12 UTC
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Eye screening study opens doors to future research
Knowledge-focused Recruiting nowThis study screens people with eye diseases to see if they can join other research studies at the National Eye Institute. No treatment is given. Participants undergo eye exams, blood tests, and other procedures to diagnose or evaluate their condition. The goal is simply to determ…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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New eye camera could catch blindness before it starts
Knowledge-focused Recruiting nowThis study tests a special camera that takes super-detailed pictures of the back of the eye (the retina). The goal is to see if this technology can find eye diseases earlier than standard methods. Up to 1,000 people aged 12 and older, with or without eye disease, will have their …
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Scientists watch and treat eye diseases to unlock their secrets
Knowledge-focused Recruiting nowThis study aims to learn more about eye diseases by observing and providing standard care to up to 1,000 people over 5 years. Participants receive regular eye exams, tests, and treatments as needed. The goal is to better understand how eye diseases progress and are inherited, not…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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German eye registry reveals shifting trends in corneal transplants
Knowledge-focused Recruiting nowThis long-term study collects data from over 100 eye clinics in Germany to see how corneal transplant surgeries have changed since 2001. Researchers track the number of surgeries, the types of procedures used, and the reasons people need them. The goal is to understand trends, no…
Sponsor: Universität des Saarlandes • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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AI-Powered summaries aim to make eye care notes clearer for patients
Knowledge-focused Recruiting nowThis study tests whether artificial intelligence can create simple summaries of eye doctor notes that are easier for patients to understand. About 460 English-speaking adults receiving eye care will get either standard notes or notes plus an AI-generated plain language summary. P…
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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New eye scanner tested on 180 volunteers – no treatment involved
Knowledge-focused Recruiting nowThis study gathers eye scan images from 180 people with healthy eyes or eye diseases like glaucoma and retinal disease. The goal is to collect data using a new optical coherence tomography (OCT) device called A10900. No treatment or medication is given. The information will help …
Sponsor: Optos, PLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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New 4D eye scanner debuts in operating room
Knowledge-focused Recruiting nowThis study tests a new 4D microscope-integrated OCT system for the first time in people during eye surgery. Researchers want to see if the system is easy to use, safe, and can clearly show eye structures. Five adults having eye surgery will take part. The goal is to improve imagi…
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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VR headset tracks eyes to unlock new diagnostic insights
Knowledge-focused Recruiting nowThis study gathers standard eye movement and pupil data from 200 healthy volunteers, children, and people with eye or brain conditions using a VR headset called neos™. The headset shows images and tracks where participants look, how their pupils react, and how their eyes move. Th…
Sponsor: machineMD AG • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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New eye camera aims to make pediatric exams easier
Knowledge-focused Recruiting nowThis study tests a new, more comfortable eye camera (WiSLO) designed for children and adults. Researchers want to see if it takes better pictures and is less bothersome than current cameras. About 42 people with or without eye disease will have their eyes photographed with both t…
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Blood test could predict arthritis severity in kids
Knowledge-focused Recruiting nowThis study is collecting blood and joint fluid samples from 300 children and young adults with juvenile idiopathic arthritis (JIA) to see if certain markers can predict how severe the disease will become. Researchers will track participants' symptoms, treatments, and joint damage…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:28 UTC