Coats plus syndrome

MONDO:0012815

Coats plus syndrome is a pleiotropic multisystem disorder characterized by retinal telangiectasia and exudates, intracranial calcification with leukoencephalopathy and brain cysts, osteopenia with predisposition to fractures, bone marrow suppression, gastrointestinal bleeding and portal hypertension. It is transmitted as an autosomal recessive disease.

Also known as: CRMCC, cerebroretinal microangiopathy with calcfications and cysts, cerebroretinal microangiopathy with calcifications and cysts

24 clinical trials for this condition and its sub-types.

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Sub-types

Cerebroretinal microangiopathy with calcifications and cysts 1 (0) Cerebroretinal microangiopathy with calcifications and cysts 2 (0) Cerebroretinal microangiopathy with calcifications and cysts 3 (0)

Broader categories

Disease (618) Nervous system disorder (217) Hereditary disease (172) Eye disorder (97) Retinal disorder (79) Human disease (14) Telomere syndrome (9) Premature aging syndrome (6) Hereditary neurological disease (5) Disorder of orbital region (3)

Trials to join now! 16 Not yet recruiting 1 Not yet finished but already full! 2 Completed 4 Terminated 1

New eye camera could spot retinal disease earlier

Knowledge-focused Not yet recruiting

This study will test a new, noninvasive camera called XyCAM CRE that measures blood flow in the back of the eye. Researchers will compare its images with standard eye tests in 350 adults with retinal disorders. The goal is to see if this camera can provide extra information to he…

Sponsor: Stuart Terry Eye Associates • Aim: Knowledge-focused

Last updated Jun 27, 2026 13:07 UTC

Coats plus syndrome

Sub-types

Broader categories

New eye camera could spot retinal disease earlier