CNS demyelinating autoimmune disease
MONDO:0006704Conditions characterized by loss or dysfunction of myelin (see myelin sheath) in the brain, spinal cord, or optic nerves secondary to autoimmune mediated processes. This may take the form of a humoral or cellular immune response directed toward myelin or oligodendroglia associated autoantigens.
894 clinical trials for this condition and its sub-types, 5 tagged with CNS demyelinating autoimmune disease itself.
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Sub-types of CNS demyelinating autoimmune disease
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Multiple sclerosis 770 trials · 858 incl. sub-types
4 sub-types
- Relapsing-remitting multiple sclerosis 265 trials
- Chronic progressive multiple sclerosis 83 trials · 115 incl. sub-types Sub-types →
- Pediatric multiple sclerosis 5 trials
- Marburg acute multiple sclerosis 0 trials
Most studied deeper sub-types
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Robot suit could help MS patients walk again – small trial underway
Symptom relief CompletedThis study explores whether a powered exoskeleton—a wearable robot—can help people with moderate to severe walking problems due to multiple sclerosis (MS) exercise and walk better. Twenty-four participants will either use the exoskeleton or do standard exercises with a fitness in…
Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Virtual reality could help spot thinking problems in MS patients
Knowledge-focused CompletedThis completed study looked at 75 people with relapsing-remitting multiple sclerosis (RRMS) who were taking the medication Aubagio. The goal was to see if virtual reality tests and real-world tasks could better detect cognitive (thinking) problems in everyday life compared to sta…
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC