Chiari malformation

MONDO:0000115

A rare genetic brain malformation characterized by displacement of the brain stem and cerebellum through the foramen magnum. It may result in hydrocephalus.

Also known as: (Arnold) Chiari malformation, Arnold-Chiari malformation, Chiari malformation

14 clinical trials for this condition and its sub-types, 13 tagged with Chiari malformation itself.

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Where it sits in the disease tree

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Part of

↑ Hereditary disease (18235)

Sub-types of Chiari malformation

Including sub-types (14) Tagged with Chiari malformation (13)

Trials to join now! 2 Not yet recruiting 1 Not yet finished but already full! 4 Completed 6

Spinal canal shape may hold key to Chiari-Related syringomyelia

Knowledge-focused Not yet recruiting

This study uses advanced MRI to examine whether a deformity in the upper spinal canal is linked to syringomyelia (fluid-filled cavities in the spinal cord) in people with Chiari malformation type I. Researchers will compare MRI scans from 50 adults with Chiari malformation, with …

Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused

Last updated Jul 24, 2026 00:00 UTC

Chiari malformation

Where it sits in the disease tree

Spinal canal shape may hold key to Chiari-Related syringomyelia