Cervical incompetence
MONDO:0005698A clinical diagnosis presenting with painless cervical dilatation and spontaneous mid-trimester birth in recurrent pregnancies in the absence of spontaneous membrane rupture, bleeding or clinical chorioamnionitis.
22 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Surgeons test safer way to remove oversized uteri without large cuts
Disease control CompletedThis study tested a new surgical method to remove very large uteri (over 20 weeks size) during total laparoscopic hysterectomy. The technique uses a cold knife to cut the uterus into a long strip that can be pulled out through the vagina, avoiding large abdominal incisions. Twent…
Phase: NA • Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Double stitch may keep babies safer: new study on weak cervix
Disease control CompletedThis study tested whether placing two stitches instead of one around the cervix during an emergency can help women with a weak cervix carry their pregnancy longer. The trial included 81 women between 16 and 25 weeks of pregnancy whose membranes were bulging out. The goal was to s…
Phase: NA • Sponsor: Centre of Postgraduate Medical Education • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Which progesterone works best to stop preterm birth? 820 women studied
Prevention CompletedThis study looked at 820 pregnant women at high risk for early labor who had a cervical stitch (cerclage). Researchers compared two ways of giving progesterone—shots into muscle versus rectal suppositories—to see which better prevents preterm birth before 37 weeks. The goal was t…
Phase: NA • Sponsor: Hina Mukhtar • Aim: Prevention
Last updated Jun 27, 2026 08:07 UTC
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Faster recovery after cervical stitch: Shorter-Acting spinal anesthetic tested
Symptom relief CompletedThis trial tests whether a shorter-acting spinal anesthetic (prilocaine) helps pregnant women recover feeling and movement faster after a cervical stitch procedure compared to the standard drug (bupivacaine). About 129 healthy pregnant women at risk of preterm loss will receive o…
Phase: PHASE4 • Sponsor: Guy's and St Thomas' NHS Foundation Trust • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
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Robot-Assisted hysterectomy shows promise in small trial
Symptom relief CompletedThis study tested the safety and effectiveness of the DEXTER robotic system in 52 patients having a hysterectomy (removal of the uterus) and related surgery for non-cancerous conditions. The main goals were to see if the robotic procedure could be completed without switching to o…
Sponsor: Distalmotion SA • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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Parenting program shows promise for easing ADHD behavior problems
Symptom relief CompletedThis study tested the Triple P parenting program for mothers of children aged 6-13 with ADHD. The program teaches strategies to reduce behavior problems and boost mothers' confidence. 67 mothers took part, with some receiving the program and others not. Researchers measured chang…
Phase: NA • Sponsor: Palestine Polytechnic University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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New device could help predict preterm birth in High-Risk pregnancies
Knowledge-focused CompletedThis pilot study tested a new device that measures cervical stiffness in 21 pregnant women at high risk for preterm birth. The goal was to see if stiffness measurements could improve risk assessment beyond standard ultrasound checks. Researchers hope this could lead to better pre…
Sponsor: Luzerner Kantonsspital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Can a new curriculum keep nursing students fit and healthy?
Knowledge-focused CompletedThis study tested different ways to teach physical activity-related health competence to nursing students in Bavaria. Over 300 students from 16 schools participated, with some schools using new teaching methods and others serving as controls. The goal was to see which approach be…
Phase: NA • Sponsor: University of Erlangen-Nürnberg • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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New stitch tool tested in robot surgeries shows promise
Knowledge-focused CompletedThis study tested a special stitch device (STRATAFIX Spiral PDS Plus) used in robot-assisted surgeries for weight loss (sleeve gastrectomy) and hysterectomy. 161 adults took part. The main goal was to see how well it controlled bleeding after stitching. Doctors also rated how eas…
Sponsor: Ethicon, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Robots vs. surgeons: which is better for hysterectomy?
Knowledge-focused CompletedThis study compared robot-assisted laparoscopy using the Senhance Surgical System to conventional laparoscopy for hysterectomy and other uterine surgeries. Researchers measured operating time, blood loss, and safety in 78 patients. The goal was to see if the robot offers advantag…
Sponsor: University Hospital Tuebingen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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New surgical order may keep vagina longer after hysterectomy
Knowledge-focused CompletedThis study tested whether starting a hysterectomy by cutting the back of the vagina (posterior colpotomy first) helps keep the vagina longer compared to the usual method. Eighty women having a hysterectomy for non-cancer reasons took part. The main goal was to measure any differe…
Phase: NA • Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC