Cerebral malaria
MONDO:0005625A sequestration of Plasmodium falciparum in the brain, which can cause coma and/or seizures.
6 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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NIH opens study to treat parasitic infections like malaria and worms
Disease control Recruiting nowThis study at the National Institutes of Health evaluates and treats people aged 3 and older with known or suspected parasitic infections, such as malaria, intestinal worms, and others. Participants receive standard medical care, not experimental treatments. The goal is to monito…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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Experimental drug DON aims to protect brains of children with cerebral malaria
Disease control Recruiting nowThis trial evaluates the safety of a single intravenous dose of DON, an experimental drug, in healthy adults, adults with uncomplicated malaria, and children aged 12 months to 14 years with cerebral malaria. Researchers will monitor side effects and measure how the drug moves thr…
Phase: PHASE1, PHASE2 • Sponsor: Douglas Postels, MD, MS • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Mass malaria treatment trial aims to wipe out hidden infections in ghanaian communities
Disease control Recruiting nowThis study will give a combination of two malaria drugs (dihydroartemisinin-piperaquine and primaquine) to entire communities in Ghana every two months for two years. The goal is to see if this approach can reduce the number of people carrying malaria parasites, even those with n…
Phase: NA • Sponsor: Noguchi Memorial Institute for Medical Research • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Could a blood transfusion save kids with severe malaria?
Disease control Recruiting nowThis study tests whether giving a whole blood transfusion can help children under 5 with severe malaria and very low platelet counts survive. The trial is enrolling 132 children in Zambia. Researchers will compare death rates and blood changes between those who get a transfusion …
Phase: NA • Sponsor: Johns Hopkins Bloomberg School of Public Health • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Can a new malaria vaccine slash childhood cases? a massive real-world test seeks answers.
Prevention Recruiting nowThis study is checking how effective the R21/Matrix-M malaria vaccine is at protecting children under 5 in Burkina Faso and Uganda, where malaria is common. Researchers will compare vaccination history in children who test positive for malaria against those who test negative. The…
Sponsor: Clinton Health Access Initiative Inc. • Aim: Prevention
Last updated Aug 08, 2026 00:03 UTC