Cerebral lipidosis with dementia
MONDO:0020143Also known as: cerebral lipidosis
38 clinical trials for this condition and its sub-types, 0 tagged with Cerebral lipidosis with dementia itself.
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Sub-types of Cerebral lipidosis with dementia
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Sandhoff disease 13 trials
3 sub-types
- Sandhoff disease, adult form 1 trial
- Sandhoff disease, infantile form 0 trials
- Sandhoff disease, juvenile form 0 trials
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Tay-Sachs disease 13 trials
4 sub-types
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Gaucher disease type I 12 trials
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Cerebrotendinous xanthomatosis 6 trials
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8 sub-types
- Juvenile neuronal ceroid lipofuscinosis 1 0 trials
- Juvenile neuronal ceroid lipofuscinosis 10 0 trials
- Juvenile neuronal ceroid lipofuscinosis 2 0 trials
- Juvenile neuronal ceroid lipofuscinosis 3 0 trials
- Juvenile neuronal ceroid lipofuscinosis 5 0 trials
- Juvenile neuronal ceroid lipofuscinosis 6 0 trials
- Neuronal ceroid lipofuscinosis 9 0 trials
- Parkinsonism due to ATP13A2 deficiency 0 trials
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Adult Krabbe disease 0 trials
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Adult neuronal ceroid lipofuscinosis 0 trials
5 sub-types
- Adult neuronal ceroid lipofuscinosis 1 0 trials
- Adult neuronal ceroid lipofuscinosis 5 0 trials
- Ceroid lipofuscinosis, neuronal, 4 (Kufs type) 0 trials
- Neuronal ceroid lipofuscinosis 11 0 trials
- Neuronal ceroid lipofuscinosis 13 0 trials
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2 sub-types
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Can a repurposed drug slow rare childhood brain diseases?
Disease control Not yet recruitingThis phase 2 trial is testing an oral drug called PLX-200 (gemfibrozil) in children aged 2 to 15 with certain lysosomal storage disorders (LSDs), including CLN2, CLN3, Sandhoff disease, and Krabbe disease. The study aims to see if the drug is safe, tolerable, and may slow the pro…
Phase 2 • Sponsor: Polaryx Therapeutics, Inc. • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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Could a simple gel boost gum healing in diabetes?
Disease control Not yet recruitingThis study tests whether adding hyaluronic acid gel to standard deep cleaning (scaling and root planing) improves gum healing in people with both diabetes and advanced gum disease. Twenty-three participants will receive the standard cleaning on all teeth, and then two gum pockets…
Sponsor: Marmara University • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Experimental gene therapy aims to halt rare childhood brain disease
Disease control Not yet recruitingThis early-phase trial tests a gene therapy for children with CLN6 Batten disease, a rare and fatal brain disorder. Twelve children will receive a single injection of the therapy into the fluid around the spinal cord. Researchers will check if it is safe and if it can slow the di…
Phase 1/2 • Sponsor: The Charlotte and Gwenyth Gray Foundation • Aim: Disease control
Last updated Jun 27, 2026 12:34 UTC
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New gene therapy hopes to fix fatal brain diseases
Disease control Not yet recruitingThis study tests a new gene therapy for GM2 gangliosidosis, which includes Tay-Sachs and Sandhoff diseases. Researchers will take blood cells from 6 patients, fix the genetic defect in the lab, and then see if these cells can help brain cells work better. The goal is to show the …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC