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Caudal regression sequence

MONDO:0017607

Caudal regression sequence is a rare congenital malformation of the lower spinal segments associated with aplasia or hypoplasia of the sacrum and lumbar spine.

Also known as: Caudal Regression Syndrome, caudal dysplasia, sacral agenesis syndrome, sacral regression syndrome

2 clinical trials for this condition and its sub-types.

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Broader categories

Disease (680) Nervous system disorder (231) Human disease (14) Neural tube defect (11) Developmental defect during embryogenesis (8) Central nervous system malformation (5) Disease by body system or component (0) Disease by developmental or physiological process (0) Disorder of development or morphogenesis (0)
Trials to join now! 1 Completed 1
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  • Can a nerve zap cure Kids' stubborn constipation?

    Disease control Completed

    This study tested two ways to stimulate sacral nerves in 48 children aged 2-17 with severe constipation and fecal incontinence that didn't improve with standard care. One group got an implanted nerve stimulator, the other a non-invasive patch. The goal was to see if either approa…

    Phase: NA • Sponsor: Friedrich-Alexander-Universität Erlangen-Nürnberg • Aim: Disease control

    Last updated Jun 26, 2026 14:55 UTC

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