Carcinoid heart disease

MONDO:0043529

Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation.

Also known as: carcinoid heart disease, carcinoid heart diseases, heart disease, carcinoid, heart diseases, carcinoid

2 clinical trials for this condition and its sub-types.

Follow this condition to get notified about new trials

Broader categories

Cardiovascular disorder (1093) Disease (717) Heart disorder (306) Human disease (15) Disease by body system or component (0)

Not yet recruiting 1 Not yet finished but already full! 1

New registry aims to unlock secrets of rare heart disease from gut tumors

Knowledge-focused Not yet recruiting

This study will create a registry of about 120 patients in Poland who have carcinoid heart disease, a rare complication of neuroendocrine tumors that damages heart valves. Researchers will collect medical records, echocardiograms, and lab results to better understand who develops…

Sponsor: National Institute of Cardiology, Warsaw, Poland • Aim: Knowledge-focused

Last updated Jun 27, 2026 09:11 UTC

Carcinoid heart disease

Broader categories

New registry aims to unlock secrets of rare heart disease from gut tumors