Biliary tract disorder
MONDO:0004868A disease involving the biliary tree.
Also known as: biliary tree disease, biliary tree disease or disorder, disease of biliary tree, disease or disorder of biliary tree, disorder of biliary tree
1005 clinical trials for this condition and its sub-types, 22 tagged with Biliary tract disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Biliary tract disorder
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Bile duct disorder 16 trials · 732 incl. sub-types
7 sub-types
- Bile duct neoplasm 41 trials · 472 incl. sub-types Sub-types →
- Non-neoplastic bile duct disorder 0 trials · 172 incl. sub-types Sub-types →
- Common bile duct disorder 0 trials · 120 incl. sub-types Sub-types →
- Cholestasis 44 trials · 91 incl. sub-types Sub-types →
- Bile duct cyst 10 trials
- Perforation of bile duct 1 trial
- Fibrosis of bile duct 0 trials
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Biliary tract neoplasm 31 trials · 627 incl. sub-types
2 sub-types
- Biliary tract cancer 244 trials · 618 incl. sub-types Sub-types →
- Bile duct neoplasm 41 trials · 472 incl. sub-types Sub-types →
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Cholelithiasis 74 trials · 108 incl. sub-types
4 sub-types
- Choledocholithiasis 40 trials
- Cholecystolithiasis 14 trials
- Gallbladder disease 1 1 trial
- Primary intrahepatic lithiasis 0 trials
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Primary biliary cholangitis 74 trials
5 sub-types
- Primary biliary cholangitis 1 3 trials
- Primary biliary cholangitis 2 0 trials
- Primary biliary cholangitis 3 0 trials
- Primary biliary cholangitis 4 0 trials
- Primary biliary cholangitis 5 0 trials
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Gallstones 36 trials · 67 incl. sub-types
1 sub-type
- Choledocholithiasis 40 trials
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Alagille syndrome 15 trials
3 sub-types
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Isolated congenital hepatic fibrosis 2 trials
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Caroli syndrome 1 trial
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Postcholecystectomy syndrome 1 trial
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Bile reflux 0 trials
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Idiopathic ductopenia 0 trials
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Isolated agenesis of gallbladder 0 trials
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Ketamine-induced biliary dilatation 0 trials
Most studied deeper sub-types
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Can a new drug rescue the liver when standard therapy fails?
Disease control CompletedThis phase 2 trial is testing an experimental drug called HTD1801 (BUDCA) in adults with primary biliary cholangitis (PBC) who haven't responded adequately to standard treatment. The goal is to see if the drug can safely lower alkaline phosphatase (ALP) levels, a key marker of li…
Phase 2 • Sponsor: HighTide Therapeutics (Hong Kong) Limited • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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Hope for rare liver disease: drug aims to ease severe itching in children
Disease control CompletedThis study tests the long-term safety of maralixibat, an oral medication, in children with progressive familial intrahepatic cholestasis (PFIC), a rare liver disease that causes intense itching. Participants who completed a prior study will receive maralixibat twice daily. Resear…
Phase 3 • Sponsor: Mirum Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New drug shows promise for babies with rare liver disorders
Disease control CompletedThis study tested the safety of a drug called maralixibat in 27 infants under 12 months old with Alagille syndrome or progressive familial intrahepatic cholestasis (PFIC), two rare liver diseases that cause bile buildup. The drug is given as an oral solution and aims to reduce bi…
Phase 2 • Sponsor: Mirum Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Liver drug maralixibat tested for Long-Term safety in rare disease patients
Disease control CompletedThis study looked at the long-term safety of a drug called maralixibat in 52 people with cholestatic liver disease, including Alagille Syndrome and other rare conditions. Participants had already taken maralixibat in an earlier study. Researchers tracked side effects and how well…
Phase 2 • Sponsor: Mirum Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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New disposable scope cover may lower infection risk in gut procedures
Disease control CompletedThis study tested two types of endoscopes used in ERCP, a procedure to treat bile duct and pancreas problems. One scope had a single-use plastic cover on its tip, while the other was a standard reusable scope. Researchers compared how well each worked and how often complications …
Sponsor: Stanford University • Aim: Disease control
Last updated Jun 26, 2026 17:07 UTC
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Which biopsy method best spots bile duct cancer?
Diagnosis CompletedThis study looked at different ways to take tissue samples from the bile duct during a procedure called ERCP. The goal was to see which method is most accurate for finding cancer. 327 adults with unclear bile duct narrowing took part. Researchers compared several biopsy technique…
Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated Jun 27, 2026 12:36 UTC
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New study maps antibiotic resistance in bile duct infections to guide smarter treatment
Knowledge-focused CompletedThis study looked at 1435 patients with acute cholangitis (a bile duct infection) who had an ERCP procedure. Researchers analyzed bile samples to understand which bacteria were causing the infections and how resistant they were to antibiotics. The goal was to find patterns that c…
Sponsor: Emergency County Hospital Pius Brinzeu; Timisoara, Romania • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Colombian hospital study reveals gaps in gallbladder care
Knowledge-focused CompletedThis study looked back at the medical records of 609 people treated for gallbladder inflammation (cholecystitis) in Villavicencio, Colombia, between 2019 and 2022. The goal was to understand how quickly patients received care, what treatments they got, and how many had complicati…
Sponsor: Hospital Departamental de Villavicencio • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC