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Autosomal recessive congenital ichthyosis 3

MONDO:0011680

Any autosomal recessive congenital ichthyosis in which the cause of the disease is a mutation in the ALOXE3 gene.

Also known as: ARCI3, autosomal recessive congenital ichthyosis type 3, ichthyosis, congenital, autosomal recessive type 3, collodion baby, self-healing, ichthyosis, congenital, autosomal recessive 3, ichthyosis, lamellar, 5, ichthyosis, lamellar, 5, formerly

3 clinical trials for this condition and its sub-types.

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Broader categories

Disease (680) Hereditary disease (176) Skin disorder (132) Eye disorder (102) Human disease (14) Ichthyosis (12) Hereditary skin disorder (6) Inherited ichthyosis (6) Autosomal recessive disease (4) Lamellar ichthyosis (4)
Not yet finished but already full! 1 Completed 1 Terminated 1
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  • New ointment shows promise for rare skin condition

    Disease control Completed

    This Phase 3 study tested an ointment called TMB-001 in 153 people aged 6 and older with X-linked or ARCI ichthyosis, conditions that cause dry, scaly, and cracked skin. Participants applied the ointment or a placebo daily for 12 weeks, with some continuing for maintenance. The g…

    Phase: PHASE3 • Sponsor: LEO Pharma • Aim: Disease control

    Last updated Jun 27, 2026 12:36 UTC

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