Atypical progressive supranuclear palsy syndrome
MONDO:0020488Atypical progressive supranuclear palsy (atypical PSP) is a group of clinical syndromes associated with underlying PSP-tau pathology, that do not conform to the classic presentation of PSP (Richardson syndrome), a rare late-onset neurodegenerative disease. The group comprises PSP-Parkinsonism (PSP-P), PSP-Pure akinesia with gait freezing (PSP-PAGF), PSP-corticobasal syndrome (PSP-CBS) and PSP-progressive non fluent aphasia (PSP-PNFA).
Also known as: atypical PSP syndrome
16 clinical trials for this condition and its sub-types.
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Broader categories
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Could a common drug slow down this rare brain disease?
Disease control OngoingThis phase 2 trial tests whether glycerol phenylbutyrate (GPB) can slow corticobasal syndrome (CBS), a rare and fast-progressing brain disease. 32 adults with CBS will receive either GPB or a placebo for 26 weeks. The main goal is to see if GPB lowers levels of a nerve damage mar…
Phase: PHASE2 • Sponsor: Technical University of Munich • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Can a simple muscle zap boost pain relief for back pain sufferers?
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether adding a daily 30-minute muscle stimulation session can improve pain control and quality of life for people who already have a spinal cord stimulator (BurstDR) for chronic back pain. Sixty adults with failed back surgery syndrome or persistent spinal p…
Phase: NA • Sponsor: Jessa Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:10 UTC