Astrocytoma (excluding glioblastoma)
MONDO:0019781A tumor of the brain or spinal cord showing astrocytic differentiation. It includes the following clinicopathological entities: pilocytic astrocytoma, diffuse astrocytoma, anaplastic astrocytoma, pleomorphic xanthoastrocytoma, and subependymal giant cell astrocytoma.
Also known as: astrocytoma
1606 clinical trials for this condition and its sub-types, 116 tagged with Astrocytoma (excluding glioblastoma) itself.
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Sub-types of Astrocytoma (excluding glioblastoma)
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Anaplastic astrocytoma 53 trials · 101 incl. sub-types
3 sub-types
- IDH-mutant anaplastic astrocytoma 10 trials · 49 incl. sub-types Sub-types →
- IDH-wildtype anaplastic astrocytoma 3 trials
- High-grade astrocytoma with piloid features 0 trials
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Low-grade astrocytoma 5 trials · 41 incl. sub-types
5 sub-types
- Diffuse astrocytoma 25 trials · 28 incl. sub-types Sub-types →
- Pilocytic astrocytoma 12 trials · 15 incl. sub-types Sub-types →
- Pleomorphic xanthoastrocytoma 7 trials
- Subependymal giant cell astrocytoma 1 trial
- Pituicytoma 0 trials
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Brain astrocytoma 2 trials · 5 incl. sub-types
4 sub-types
- Cerebellar astrocytoma 2 trials Sub-types →
- Diencephalic astrocytomas 0 trials · 1 incl. sub-types Sub-types →
- Brain stem astrocytic neoplasm 0 trials Sub-types →
- Cerebral astrocytoma 0 trials Sub-types →
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Spinal cord astrocytoma 0 trials
Most studied deeper sub-types
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Oral Brain-Penetrating drug tested against aggressive IDH1-Mutant gliomas
Disease control Not yet recruitingResearchers are testing an oral drug called safusidenib in adults newly diagnosed with IDH1-mutant grade 3 oligodendroglioma or astrocytoma, two types of brain tumor. Safusidenib is designed to cross into the brain and block the mutated IDH1 enzyme that drives these tumors. All 2…
Phase 2 • Sponsor: University of Zurich • Aim: Disease control
Last updated Sep 21, 2026 22:00 UTC
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Radioactive tiles target brain tumors in frail patients
Disease control Not yet recruitingResearchers are testing whether GammaTile, a collagen tile embedded with radioactive cesium-131 seeds, can be safely placed in the brain after surgery for malignant glioma. The trial enrolls elderly or frail patients with newly diagnosed or recurrent tumors. The main goals are to…
Phase 2 • Sponsor: University of California, Irvine • Aim: Disease control
Last updated Sep 17, 2026 00:00 UTC
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Targeted pill aims to stall a common brain Tumor's growth
Disease control Not yet recruitingThis study tests whether the experimental drug safusidenib can slow or stop the growth of a type of slow-growing brain tumor called grade 2 glioma that has a specific genetic change (IDH1 mutation). Participants have had surgery but no other treatments like chemotherapy or radiat…
Phase 3 • Sponsor: Nuvation Bio Inc. • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
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New group program aims to boost Well-Being in brain cancer patients
Symptom relief Not yet recruitingThis study tests a new group self-management program for adults with brain cancer. The goal is to see if the program is practical and helps improve mental health and quality of life more than standard care. Researchers will compare changes in well-being between the group program …
Sponsor: University of Colorado, Denver • Aim: Symptom relief
Last updated Jun 27, 2026 13:03 UTC
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Brain tumor study aims to clear up scans by shifting chemo timing
Knowledge-focused Not yet recruitingThis study tests giving chemotherapy before radiation for people with high-grade gliomas, a type of aggressive brain tumor. The goal is to see if this approach works well and makes MRI scans easier to read, since radiation can change how the brain looks. About 70 adults aged 18-8…
Phase 2 • Sponsor: The Cooper Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC