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Apolipoprotein A-I deficiency

MONDO:0700513

A lipoprotein metabolism disorder characterized biochemically by complete absence of apolipoprotein AI and extremely low plasma high density lipoprotein (HDL) cholesterol, and clinically by corneal opacities and xanthomas complicated with premature coronary heart disease (CHD).

12 clinical trials for this condition and its sub-types.

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Sub-types

Hypoalphalipoproteinemia, primary, 1 (2) Hypoalphalipoproteinemia, primary, 2 (0) Hypoalphalipoproteinemia, primary, 2, intermediate (0)

Broader categories

Disease (618) Metabolic disease (215) Human disease (14) Hypoalphalipoproteinemia (1) Disease by developmental or physiological process (0)

Trials to join now! 10 Not yet recruiting 1 Completed 1

Massive diabetes registry aims to unlock secrets of metabolic disease

Knowledge-focused Not yet recruiting

This 10-year observational study will follow 10,000 adults with diabetes, metabolic disorders, and related conditions like high blood pressure and fatty liver disease. Researchers will collect routine medical data to identify markers of disease severity and activity. The goal is …

Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused

Last updated Jun 27, 2026 07:53 UTC