Alexander disease

MONDO:0008752

Alexander disease (AxD) is a rare neurodegenerative disorder of the astrocytes comprised of two clinical forms: AxD Type I and Type II manifesting with various degrees of macrocephaly, spasticity, ataxia and seizures and leading to psychomotor regression and death.

Also known as: Alexander disease, AxD, ALXDRD, alexanders leukodystrophy, megalencephaly in infancy accompanied by progressive spasticity and dementia

19 clinical trials for this condition and its sub-types.

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