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127005 trials found · Page 6247 of 6351
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Breakfast vs. drug: does a fatty meal change how ABBV-101 works?
Knowledge-focused CompletedThis study will assess the effect of food (high fat) on oral ABBV-101 and how ABBV-101 moves through the body in healthy adult participants
Phase 1 • Sponsor: AbbVie • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Tucked arms study tests muscle monitor accuracy
Knowledge-focused By invitation onlyThe purpose of this research is to compare the performance of acceleromyograph and electromyograph-based quantitative neuromuscular monitors when the arms are tucked for surgical positioning.
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Drug combo safety checked in healthy volunteers
Knowledge-focused CompletedA Phase 1 Study to evaluate the safety, PK/PD, drug-drug interaction(DDI) of Epaminurad and C2406 in Healthy Volunteers
Phase 1 • Sponsor: JW Pharmaceutical • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC
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Takeda tests new concentrated antibody shot against existing treatment
Knowledge-focused CompletedThe main aim of this study is to understand how the body absorbs, processes, and removes (known as pharmacokinetics or PK) TAK-881 and HyQvia, after they are given as a single injection under the skin in healthy adults. Study participants will receive a single dose of TAK-881 or…
Phase 1 • Sponsor: Takeda • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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New drug ENX-205 put to the test in healthy people
Knowledge-focused CompletedThis is a two-part study designed to evaluate the safety, tolerability, pharmacokinetics (PK), and receptor occupancy (RO) of ENX-205 in healthy adult participants in a double-blind placebo-controlled, single ascending dose (SAD) study (Part 1) and an open-label, single-dose, pos…
Phase 1 • Sponsor: Engrail Therapeutics INC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC
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Mock interviews boost nursing Students' career confidence, study finds
Knowledge-focused CompletedThis single-group pretest-posttest pilot study evaluates the effect of a mock interview workshop, grounded in Self-Determination Theory, on career decision-making self-efficacy (CDMSE) and interview performance among first-year undergraduate nursing students in China. The 6-hour …
Sponsor: China Medical University, China • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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New study tests digital workarounds for dental implant scanning
Knowledge-focused CompletedThis methodological clinical study aims to evaluate digital workflows used for the intraoral digitalization of cement-retained implant abutments in situations where implant impression components are unavailable and abutment replacement is not feasible. Three digital impression wo…
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated Sep 04, 2026 00:00 UTC
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Healthy volunteers help uncover drug interaction secrets
Knowledge-focused CompletedThe purpose of this study is to learn how carbamazepine changes how the body processes PF-07220060 in the body of healthy adults. This study will happen in 2 periods. The purpose of Period 1 of the study is to understand how the medicine is changed and eliminated from the body a…
Phase 1 • Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Early safety check for experimental drug BMS-986460
Knowledge-focused CompletedThe purpose of this study is to assess the safety, tolerability, drug levels, and relative bioavailability of alternate formulations of BMS-986460 in healthy adult male participants.
Phase 1 • Sponsor: Bristol-Myers Squibb • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Pfizer tests drug interactions in healthy volunteers
Knowledge-focused CompletedThe purpose of this study is to learn about the effect of cyclosporine, an immunosuppressant (medicine that suppresses the immune system), on the pharmacokinetics (PK) of PF-07328948 in healthy participants (Part A). The study may also estimate the effect of clarithromycin, an an…
Phase 1 • Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Healthy volunteers test generic vs. brand drug equivalence
Knowledge-focused CompletedProspective, longitudinal, single-dose, randomized, open-label, crossover 2x2, two treatments, two periods, two sequences controlled clinical study
Phase 1 • Sponsor: ADIUM • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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High blood pressure drug trial halted after just one patient
Disease control Stopped earlyThis is a Phase 1, first-in-human, randomized, double-blind, placebo-controlled, study to assess the safety, tolerability, Pharmacokinetics (PK), and pharmacodynamics (PD) of a single dose of ART101 administered via subcutaneous injection to hypertensive adult participants. An an…
Phase 1 • Sponsor: Arnatar Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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New protocol aims to improve organ preservation in deceased donors
Knowledge-focused CompletedThe goal of this observational study is to describe the details of a controlled administration strategy of cold preservation solution or oxygenated cold preservation solution at the end of Abdominal Normothermic Regional Perfusion (A-NRP) in Controlled Donation afeter Circulatory…
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Smart inhaler study scrapped before it even started
Knowledge-focused CancelledDevice: EDDIS-IDDS (Enhanced Digital Dose Inhalation Delivery System) - a portable, breath-actuated, digitally monitored system for precision delivery of inhaled agents with automated recording of inspiratory volume, flow, duration, and breath-hold parameters. Drug: 99mTc-DTPA…
Phase 1 • Sponsor: Andrey Petrov • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Quick neck fix? study tests One-Time exercise for neck pain relief
Knowledge-focused CompletedThe goal of this observational study is to evaluate the immediate effects of cranio-cervical flexion exercises and correct posture training on upper extremity and trunk kinematics during functional activities in young adults with neck pain. The main questions it aims to answer a…
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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New CT scanner put to the test: does it satisfy users?
Knowledge-focused CompletedThe purpose of this study is to assess the satisfaction of the common functions, the operation convenience, and the whole system stability, and the safety of CT 5400 RT System.
Sponsor: Philips Clinical & Medical Affairs Global • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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New nasal spray for brain diseases passes first safety check in healthy volunteers
Knowledge-focused CompletedA Phase 1, Randomized, Double-Blinded, Placebo-Controlled study to Evaluate the Safety, Tolerability,and Pharmacokinetics of Single and Multiple Ascending Doses of CBT101 given intranasally in Healthy Male Subjects.
Phase 1 • Sponsor: Ceres Brain Therapeutics • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Can a nudge get you to join a study?
Knowledge-focused CompletedThe goal of this clinical trial is to examine the effect of using behavioral nudges in recruitment into a minimal risk interview study among healthy adult volunteers. Individuals will be randomized to receive recruitment materials that do or do not contain a set of behavioral nu…
Sponsor: University of Utah • Aim: Knowledge-focused
Last updated Aug 02, 2026 00:00 UTC
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Healthy volunteers test new drug VIS954 for safety
Knowledge-focused CompletedThe purpose of this study is to evaluate the safety, pharmacokinetics, and pharmacodynamics of multiple doses of VIS954 compared with placebo in healthy adult participants.
Phase 1 • Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Experimental DME pill trial ends early after just one patient
Disease control Stopped earlyA non-randomized study evaluating the safety of an orally administered inflammasome inhibitor, K9, for the treatment of diabetic macular edema (DME).
Phase 1 • Sponsor: Michelle Abou-Jaoude • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC