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127005 trials found · Page 6244 of 6351
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Prostate cancer study pulled before it began
Knowledge-focused CancelledThis is an open-label, multicenter, interventional study in racially self-identified black or ethnically self-identified hispanic and racially self-identified white or native American participants with metastatic castration-resistant prostate cancer whose tumors demonstrate molec…
Phase 2 • Sponsor: Latin American Cooperative Oncology Group • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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Heart failure drug trial pulled before it even started
Disease control CancelledThe primary objective of the study is to compare relative changes in blood N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels after 30 days of treatment in participants with worsening heart failure (WHF), who are treated with either OPC-131461 or placebo.
Phase 2 • Sponsor: Otsuka Pharmaceutical Development & Commercialization, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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Healthy volunteers test drug interaction in Early-Stage trial
Knowledge-focused CompletedThe main objective of this trial is to investigate the effect of erythromycin, a moderate CYP3A4 inhibitor on the pharmacokinetics of BI 1291583 at steady state.
Phase 1 • Sponsor: Boehringer Ingelheim • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:23 UTC
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Did doctors get the memo? study checks depakine safety alerts in saudi arabia
Knowledge-focused CompletedA cross-sectional, national, multicenter, survey-based study to assess the effectiveness of Risk Minimization Measures related to Depakine® (sodium valproate) in Saudi Arabia. The end of study is defined as the end of the data collection period. No intervention will be administer…
Sponsor: Sanofi • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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New drug SR750 tested in healthy volunteers – no cure expected
Knowledge-focused CompletedThis is a randomized, double-blind, placebo-controlled phase I bridging study to evaluate the PK, safety and tolerability of SR750 (formulation F1) in Chinese healthy subjects.
Phase 1 • Sponsor: Shanghai SIMR Biotechnology Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Can a 'Fishbowl' classroom activity boost nursing skills?
Knowledge-focused CompletedBackground: Breathing and coughing exercises are fundamental components of nursing care in the management of chronic respiratory diseases, and the way students learn these skills is closely related to their clinical skill development. Active learning approaches that combine obse…
Sponsor: Zeynep Yılmaz • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Can a drink trick your appetite hormones? small study investigates
Knowledge-focused CompletedThe primary objective of this study is to evaluate post-meal appetite hormones and appetite ratings, assessed using visual analog scale (VAS) questionnaires, in response to proprietary beverages in generally healthy adults.
Sponsor: Shaklee Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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New drug UCB0022 tested for safety in healthy people
Knowledge-focused CompletedThe primary purpose of this study is to assess the safety and tolerability of oral glovadalen (UCB0022) in healthy Caucasian, Japanese, and Chinese participants.
Phase 1 • Sponsor: UCB Biopharma SRL • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:01 UTC
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Kidney health may change how body handles experimental drug ESK-001
Knowledge-focused CompletedThis a phase 1, open label, single dose, parallel cohort study to determine the pharmacokinetics (PK) of study drug (ESK-001) in healthy volunteer participants, and participants with mild, moderate, and severe renal impairment.
Phase 1 • Sponsor: Alumis Inc • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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New muscle relaxant injection passes first safety check in healthy volunteers
Knowledge-focused CompletedThis is a single-center, open-label and dose-escalation study to evaluate the safety, tolerability and dose-response relationship of HRS-9190 in healthy adults.
Phase 1 • Sponsor: Jiangsu HengRui Medicine Co., Ltd. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Needle-Free brain pressure test for kids hits snag before starting
Diagnosis CancelledIntracranial pressure (ICP) monitoring is indicated in a wide range of neurological diseases. The combination of a linear ultrasound array with an integrated pressure sensor into a single handheld probe (ICP Probe) enables the user to precisely and non-invasively estimate blood p…
Sponsor: Compremium AG • Aim: Diagnosis
Last updated Jun 27, 2026 12:23 UTC
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New drug LAE102 put to the test in healthy women
Knowledge-focused CompletedThe purpose of the study is to evaluate the safety, tolerability and pharmacokinetics (PK) of LAE102 in healthy postmenopausal women
Phase 1 • Sponsor: Laekna Limited • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Healthy volunteers test new immune globulin injection method
Knowledge-focused CompletedThe main aim of this study is to check how well healthy adults can tolerate TAK-881 with different dosing schedules. During the study, participants will receive one infusion of TAK-881 under the skin (subcutaneous \[SC\] infusion) on Day 1 at a lower dose level followed by parti…
Phase 1 • Sponsor: Takeda • Aim: Knowledge-focused
Last updated Aug 19, 2026 00:00 UTC
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Risankizumab injector study completed – no major breakthrough expected
Knowledge-focused CompletedThis study will assess the pharmacokinetics and relative Bioavailability of risankizumab following subcutaneous (SC) administration with on-body Injector in Healthy Adult Participants.
Phase 1 • Sponsor: AbbVie • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Breakfast vs. pill: does food change how this drug works?
Knowledge-focused CompletedThis study will explore the potential effects of high-fat meal on the plasma pharmacokinetics (PK) of CRS3123 when administered as a single oral dose of 200 mg in healthy adult participants.
Phase 1 • Sponsor: Crestone, Inc • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Withdrawn HIV stigma study aimed to help young gay men in ghana slums
Knowledge-focused CancelledThe primary objective of this study is to adapt and evaluate the feasibility of "Lafiya," which means "Wellness" in Hausa, a multilevel intersectional stigma \& discrimination (ISD) and HIV testing intervention, to a status-neutral intervention to increase HIV testing, PrEP, and …
Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Caregiver struggles: a deep dive into peritoneal dialysis support
Knowledge-focused CompletedThis study aimed to explore the subjective opinions and perspectives of peritoneal dialysis caregivers regarding the caregiver burden they experience.
Sponsor: Yuzuncu Yil University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Could a simple instruction change how you report depression?
Knowledge-focused OngoingWe want to explore if emphasizing certain instructions (i.e. "bothered by") will affect the way participants respond to a questionnaire.
Sponsor: University of California, Irvine • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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New drug nacresertib tested in healthy people for first time
Knowledge-focused CompletedThe objectives for this 2 Part study are to assess the safety, tolerability, and pharmacokinetics following single ascending oral doses of nacresertib in healthy adult participants (Part 1) and to assess the safety, tolerability, and pharmacokinetics following multiple ascending …
Phase 1 • Sponsor: AbbVie • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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Can a special drink keep you more hydrated than water?
Knowledge-focused CompletedIn this study, the investigators want to assess the effects of a new beverage containing whey protein and glycerol (two different dosages) on hydration status in healthy adults when compared to the control (water). This is a single-center, double-blinded, 3 arm cross-over random…
Sponsor: Société des Produits Nestlé (SPN) • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC