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127005 trials found · Page 6133 of 6351
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Syringe showdown: does a prefilled device deliver drug as well as a vial?
Knowledge-focused CompletedThe purpose of this study is to assess how fast pegilodecakin gets into the blood stream and how long it takes the body to remove it, when given as a solution formulation via a prefilled syringe (PFS) versus from a vial drawn into a conventional syringe. Information about side ef…
Phase 1 • Sponsor: Eli Lilly and Company • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC
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Rare gut Condition's hidden impact on Kids' brains revealed
Knowledge-focused CompletedHirschsprung's disease (HD) is a rare congenital disease (1:5000) characterized by neonatal functional low bowel obstruction that is caused by aganglionosis of the distal bowel. HD treatment consists in surgery of colonic reduction in the early childhood, requiring afterward a lo…
Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Snack showdown: which treat tames hunger and blood sugar best?
Knowledge-focused Recruiting nowThe purpose of the present study was to determine the effects of different type of snack consumption on postprandial satiety, glucose, insulin, antioxidant capacity and anxiety in healthy subjects.
Sponsor: San Diego State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Sleep apnea may be overlooked in type 1 diabetes
Knowledge-focused CompletedObstructive sleep apnea (OSA) and Type 2 diabetes are two frequent diseases that occur in adult population. The prevalence of OSA is higher in people with Type 2 diabetes compared with the general population7 ; in addition, the OSA syndrome is almost assessed in obese type 2 diab…
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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7-Year checkup: do implant dentures hold up?
Knowledge-focused CompletedABSTRACT Statement of the problem: Insufficient long-term retrospective data is evaluating marginal bone loss and retention of four-implant Locator-retained mandibular overdentures. Purpose: To assess marginal bone loss and retention of four-implant Locator-retained mandibular o…
Sponsor: Mansoura University • Aim: Knowledge-focused
Last updated Aug 15, 2026 00:00 UTC
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Cancer Patients' blood clot care under the microscope
Knowledge-focused Recruiting nowThe goal of this research study is to learn about the quality of life, experiences with treatment, and healthcare costs of patients who are receiving long-term treatment for venous thromboembolism (VTE) that is related to cancer. This is an investigational study. Up to 260 parti…
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Study reveals hidden breathing issues in severe MS patients
Knowledge-focused CompletedThe purpose of this study is to describe respiratory disorders in patients with severe multiple sclerosis (EDSS from 6.5).
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Dental implant showdown: which connection design saves more bone?
Disease control CompletedThis study designed as a randomized controlled split-mouth trial will be conducted at the Dental Clinic of the University of Valencia. The aim will be to assess differences in clinical, radiological and microbiological outcomes between implants with 2 different connections: inter…
Sponsor: University of Valencia • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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Joint pain from cancer drug measured in new study
Knowledge-focused CompletedSelf-administered questionnaire survey to determine the presence or absence of joint pain during bevacizumab treatment for lung, ovarian, colorectal cancers. The principal end-point is the frequency of arthralgia after 6 months of treatment with Bevacizumab.
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Probiotics in pregnancy: tiny study tracks Baby's gut bugs
Knowledge-focused CompletedThis study aim to evaluate the composition and origin of the neonatal gut microbiota after birth and Probiotic intervention. Samples were obtained from a total of 30 pregnant individuals and their offspring, divided into control group and porbiotics group. Postpartum human milk a…
Sponsor: Third Affiliated Hospital, Sun Yat-Sen University • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:56 UTC
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Hospital chat tool usage soared during pandemic
Knowledge-focused CompletedThe COVID-19 pandemic becomes a global challenge. Beneficial to being an island country and having appropriate policies, there were only few imported cases in Taiwan. However, many locally acquired cases came out in the mid of this May. The hospital policy about containing infect…
Sponsor: National Taiwan University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Peppermint power: could a simple scent prevent catheters after birth?
Symptom relief Stopped earlyThe purpose of this study is to examine the effectiveness of peppermint oil to promote voiding and reduce urinary catheterization among postpartum women.
Sponsor: Mount Carmel Health System • Aim: Symptom relief
Last updated Jun 27, 2026 09:11 UTC
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Dementia study reveals hidden cases in norway
Knowledge-focused CompletedTo investigate and make valid estimates of the occurrence of dementia and the most common subtypes of dementia in Trøndelag, and transfer these figures to estimates of the occurrence of dementia in Norway as a whole, by age, sex and severity of dementia. Furthermore, the proporti…
Sponsor: Norwegian Centre for Ageing and Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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New toothpaste promises 12-Hour fresh breath
Symptom relief CompletedTo investigate the clinical efficacy of a new toothpaste containing 0.454% stannous fluoride as compared to a regular fluoride toothpaste containing 0.76% sodium monofluorophosphate on oral malodor reduction via organoleptic scores 12 hours post-brushing overnight after 3 weeks o…
Phase 3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Healthy volunteers help unlock the Body's handling of a new drug
Knowledge-focused CompletedTo evaluate the pharmacokinetics of different dose levels and dose formulations of pegilodecakin in healthy adult participants.
Phase 1 • Sponsor: Eli Lilly and Company • Aim: Knowledge-focused
Last updated Jul 09, 2026 00:00 UTC
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App aims to get breast cancer patients moving during chemo
Symptom relief Stopped earlyEvaluate the "Bouge" digital program (smartphone application) to increase the daily physical activity of breast cancer patients
Sponsor: University Hospital, Brest • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
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New breathing test for newborns could improve lung care
Knowledge-focused OngoingThe purpose of this observational study is to measure pulmonary function in term and preterm infants with and without pulmonary disease including respiratory distress syndrome, bronchopulmonary dysplasia, transient tachypnea of the newborn, meconium aspiration syndrome, and respo…
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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3-Second fillings: new dental material tested for speed and comfort
Symptom relief CompletedThe purpose of this clinical trial is to measure the clinical outcomes of Tetric PowerFill Class I and II restorations cured in 3 seconds with the Bluephase PowerCure curing unit.
Sponsor: Ivoclar Vivadent AG • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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New study looks at how frailty affects brain injury recovery in seniors
Knowledge-focused CompletedThis multicenter prospective observational study is designed to prospectively record data on patients who are managed per institutional standard of care. The objectives of this study are to establish an aggregate database of information on baseline clinical and demographic charac…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Scientists track how walking, running, and marathons change your Blood's repair system
Knowledge-focused By invitation onlyThe purpose of this study is to detail the precise temporal changes in the APR that occur in response to exercise in order to determine the types of exercise that confer maximal reparative fibrinolysis. Published research and preliminary studies conducted in our lab suggest that …
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC