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127005 trials found · Page 5754 of 6351
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New imaging technique could help doctors predict cancer treatment response
Knowledge-focused CompletedHead and neck cancer is the sixth most frequent cancer worldwide, excluding lymphomas and skin cancer. If 18FDG PET is considered today as a standard tool in patients with head and neck squamous cell carcinoma (HNSCC) not only for tumoral or nodal staging but also for assessment …
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Allergy sufferers: new nasal spray study offers hope for symptom relief
Symptom relief CompletedThis is a comparative, open label, parallel group, non interventional study to further demonstrate the effectiveness and tolerability of Ectoin Allergy Nasal Spray. In addition the effectiveness and safety shall be compared to a Cromoglycid acid containing nasal spray. The patien…
Sponsor: Bitop AG • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Blood test could predict lupus flares
Knowledge-focused CompletedLupus erythematosus systemic is an auto-immune disease the evaluation of the activity of which remains very difficult because of an heterogeneousness of the clinical and biological symptoms. The aim of this study is to develop objective, specific and not invasive methods of evalu…
Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:27 UTC
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New brain scans could sharpen diagnosis of lewy body dementia
Knowledge-focused CompletedThe general aim of this research project is to determine the relationships between alterations of central cholinergic (ACh) and dopaminergic (DA) systems and neurobehavioral features of dementias with Lewy bodies (DLB). Both clinical and neurochemical data support the view that …
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Massive cancer registry aims to unlock genetic secrets of bladder cancer
Knowledge-focused OngoingThis study is being done to create a registry to help us learn more about urinary and other cancers. This will let us look at large groups of people who do and do not have this kind of cancer. The investigators will look at risk factors to learn more about how these impact cance…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Aug 26, 2026 00:00 UTC
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Which breathing tube causes the least pain? study compares three devices
Symptom relief CompletedThe investigators hypothesize that incidence of pharyngolaryngeal postoperative pain caused by the I-gel and LMA-Suprême devices will be ≤ 5%
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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New study measures how brain radiation affects thinking and daily life
Knowledge-focused CompletedBackground: * There are no standardized sets of tests to measure changes in neuropsychological functioning in patients treated for brain metastasis (cancer that has spread beyond the original site to the brain). * Neuropsychological function has an important effect on quality of…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Colon cancer clues: DNA repair status may guide surgery decisions
Knowledge-focused CompletedThis study analyzed the differences in clinical baseline features and survival outcomes between pMMR and dMMR patients. The aim is to evaluate the impact of MMR status on overall survival and disease-free survival of colorectal patients, and to explore the population exempt from …
Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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New antiviral pill could shorten your next cold
Disease control CompletedThis randomized, single blind clinical study was conducted to investigate the clinical efficacy and safety of the drug Amizon (enisamium iodide), in comparison with placebo for the treatment of patients with acute respiratory viral infections (ARVI), including influenza. Enisamiu…
Phase 2/3 • Sponsor: Joint Stock Company "Farmak" • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Scientists track early HIV to unlock secrets of the virus
Knowledge-focused Recruiting nowTo describe clinical, immunological, and virological characteristics of persons with acute HIV infection 1. To describe demographics and behavioral risk factors for those identified with acute HIV infection 2. To describe neurocognitive function and neuroimaging findings in acut…
Sponsor: SEARCH Research Foundation • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Could early aging in diabetes signal hidden heart risk?
Knowledge-focused CompletedThe potential clinical implications of this study are to optimise the selection of a population at risk for developing a diabetic cardiomyopathy among diabetic patients in order to develop early therapeutic strategies to prevent the left ventricular remodelling. Therefore, the o…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:55 UTC
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Hopkins launches massive breast cancer data bank
Knowledge-focused OngoingThe Breast Cancer Program Longitudinal Repository (BCPLR) is being established to fulfill the research mission of the Breast Cancer Program at Johns Hopkins and to serve investigators affiliated with it - to develop a repository of specimens with corresponding characteristics fro…
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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Cystic fibrosis diabetes mystery: why does it sometimes go away?
Knowledge-focused CompletedFor some years, the investigators observe an increase of the arisen of diabetes in cystic fibrosis patients However, this diabetes may be reversible. The investigators speak about " Cystic fibrosis related diabetes.". The objective of this project, is to know better what facilita…
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:08 UTC
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Anemia drug MIRCERA studied in kidney patients before dialysis
Disease control CompletedAn observational, longitudinal, multi-center, non-interventional study in participants with chronic kidney disease (CKD) stage 3-4, assessed by Modification of Diet in Renal Disease (MDRD) to collect data regarding safety and efficacy in participants with pre-dialysis situation w…
Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Jun 26, 2026 16:55 UTC
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Scientists hunt for genes behind rare kidney condition
Knowledge-focused CompletedEvaluation of the frequency of familial cases of renal HYPODYSPLASIA
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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New blood thinner tested for rare clotting disorder
Disease control CompletedThe purpose of this study is to collect data on the clinical management of Argatroban in patients with suspected or confirmed heparin-induced thrombocytopenia Type II, with or without ongoing thrombosis who require parenteral antithrombotic therapy
Phase 2 • Sponsor: Tanabe Pharma Corporation • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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7,000 volunteers needed to crack the genetic code of keloids.
Knowledge-focused Recruiting nowKeloids have a strong genetic component. The goal of this study is to identify genes and regulatory elements on chromosomes that are the cause for keloids or contribute to keloid scarring.
Sponsor: UConn Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Scientists hunt for cherubism genes in 600-Person study
Knowledge-focused Recruiting nowThe goal of this research study is to identify genes and regulatory elements on chromosomes that cause cherubism. Together with the investigators collaborators the investigators also study blood samples and tissue samples from patients to learn about the processes that lead to th…
Sponsor: UConn Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Immune cell clues in colon cancer could forecast recurrence risk
Knowledge-focused CompletedColorectal cancer (CRC) is one of the most common cancers in France (36,000 new cases / year) and nearly 16,000 people die each year from this disease. The lymph node involvement of the surgical specimen is today the main tool on which is based the adjuvant treatment decision aft…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Scientists hunt for genes behind rare skin condition
Knowledge-focused Recruiting nowThe goal of this research study is to identify genes and regulatory elements on chromosomes that cause ACC. The investigators also study tissue samples from patients to learn about the processes that lead to this disorder.
Sponsor: UConn Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC