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116076 trials found · Page 5191 of 5804
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Can a training program help nurses and social workers support caregiving families?
Knowledge-focused OngoingThe purpose of this study is to provide a communication training program to inpatient nurses and social workers at Memorial Sloan Kettering Cancer Center in order to help them assist caregiving families. The importance of this training program is that it aims to teach nurses and …
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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New Light-Based test aims to catch deadly newborn gut disease early
Diagnosis TerminatedThe main objective is to evaluate the interest of cerebro-splanchnic oxygenation ratio (CSOR) for early diagnosis of necrotizing enterocolitis (NEC) in neonates with rectal bleeding and/or abdominal distension. CSOR will be determined using near infrared spectroscopy (NIRS).
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Diagnosis
Last updated Jun 27, 2026 14:00 UTC
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Gene hunt for rare cancers aims to unlock new treatments
Knowledge-focused Recruiting nowThis research trial studies the use of targeted genomic analysis of blood and tissue samples from patients with cancer. Genomic sequencing is a laboratory method that is used to determine the entire genetic makeup of a specific organism or cell type. Genomic sequencing can be use…
Sponsor: Rutgers, The State University of New Jersey • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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New study tracks Cancer's lasting impact on Women's sexual and fertility health
Knowledge-focused Recruiting nowThe purpose of this study is to see how cancer treatment affects sexual and reproductive function. The patient will also be asked to participate in blood draws to see if and how cancer treatment affects the ovaries and the ability to have children (fertility). These blood draws a…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Lab study reveals how HIV drug crosses the placenta
Knowledge-focused CompletedThe purposes of this study are to determine whether transporters expression levels and drug interaction between TDF and FTC could contribute to modulate the placental transfer of this drug or. To test this hypothesis, an ex vivo model known as "the perfused ex vivo cotyledon mode…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Will your new knee last 15 years? study tracks attune implant survivorship
Knowledge-focused OngoingThis post-marketing investigation will evaluate the long term (up to 15 years) survivorship of the Attune Primary Knee Prosthesis in patients with non-inflammatory degenerative joint disease. Data from Subjects who receive one of four knee configurations will be pooled to establi…
Phase: NA • Sponsor: DePuy International • Aim: Knowledge-focused
Last updated Jul 08, 2026 00:00 UTC
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Veterans' lung health under the microscope: new database launches
Knowledge-focused Recruiting nowThe purpose of this research study is to establish a research database and biorepository for patients at National Jewish Health (NJH) who served in Operation Iraqi Freedom (OIF) or Operation Enduring Freedom (OEF). This study will also include civilian contractors who worked as p…
Sponsor: National Jewish Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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800 kids monitored for arthritis drug risks over years
Knowledge-focused OngoingThe purpose of this study is to examine the long-term safety of Abatacept for the treatment of juvenile idiopathic arthritis (JIA) with particular in interest in the occurrence of serious infections, autoimmune disorders, and malignancies.
Sponsor: Bristol-Myers Squibb • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC
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One patient gets experimental enzyme to fight rare kidney disease
Disease control CompletedBackground: * High density lipoprotein (HDL), or good cholesterol, moves cholesterol from the artery walls back to the liver. A blood enzyme known as LCAT maintains HDL levels and helps it remove cholesterol from the body. Familial LCAT deficiency (FLD) is a genetic disease that…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
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Psoriasis study probes hidden heart risks
Knowledge-focused CompletedBackground: \- Cardiometabolic diseases are medical disorders that can occur together and affect the heart. They increase the risk of developing heart disease and diabetes. One disorder, psoriasis, is an inflammation that mostly affects the skin but can affect the entire body. A…
Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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New toothpaste study aims to soothe sensitive teeth
Symptom relief CompletedThe purpose of this study is to compare the clinical efficacy of test fluoride dentifrice in reducing Dentin Hypersensitivity (DH) with that of a standard fluoride dentifrice, as measured by evaporative air sensitivity after 12 weeks twice daily brushing.
Phase: NA • Sponsor: HALEON • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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5,000 seniors tracked for a decade to unlock secrets of healthy aging
Knowledge-focused CompletedWith the third wave of the Transitions and Old Age Potential (TOP) study, the longitudinal study of initially 5,002 individuals was completed in 2019. Initial findings were published in 2020 through a brochure, policy brief, and methodological report, and presented publicly. The …
Sponsor: Jacobs University Bremen gGmbH • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Light-Based device may predict amputation healing
Knowledge-focused Terminated50 patients will be included for each of the 2 procedures: \- For procedure 1: Patients will be selected during multidisciplinary consultations for amputees who are stabilized with their definitive prosthesis and have returned to their usual place of residence. The aim of this p…
Phase: NA • Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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New tests could help spot hidden blood disorder in seniors
Knowledge-focused CompletedIt is about a multicentric study prospective of more than patients' 60 years with a thrombopenia isolated of less than 100 G/L blood platelet without cause found to estimate so certain examinations realized in the diagnosis (medullary cytogenetics, dosage of the TPO, the Anti-pla…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Brain scans reveal secrets of tone deafness
Knowledge-focused CompletedThe project studies auditory deficits in congenital amusia at the behavioral and neurophysiological levels. The auditory processes investigated are pitch discrimination, short-term memory, sound-induced emotions. To characterize auditory deficits in the amusic population, neurop…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:32 UTC
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New biopsy technique could spare patients from major surgery
Diagnosis CompletedImpact of screening nodes mediastinal by PET, at different times of the management of cancer disease, remain unclear. Benefits of combined PET and puncture with echoendoscopy for the diagnosis subsequent therapeutic management should be evaluated in these different contexts. We…
Phase: NA • Sponsor: Institut Bergonié • Aim: Diagnosis
Last updated Jun 26, 2026 12:40 UTC
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Scientists hunt for genes behind rare eye conditions
Knowledge-focused Recruiting nowBackground: \- Uveal coloboma is a condition where the eye does not form normally. It occurs early in the fetus s development during pregnancy. It can lead to different kinds of eye problems, including blindness. Uveal coloboma is part of a spectrum of developmental eye conditio…
Sponsor: National Eye Institute (NEI) • Aim: Knowledge-focused
Last updated Jul 19, 2026 00:00 UTC
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Inner ear secrets: study aims to predict who will hear better with hearing aids
Knowledge-focused CompletedUnderstanding speech is essential for good communication. Individuals with hearing loss and poor speech discrimination often have little success with hearing aids because amplifying sound improves audibility, but not clarity of the speech signal. The purpose of this study is to d…
Sponsor: Steward St. Elizabeth's Medical Center of Boston, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Vitamin d deficiency common in heart failure patients – does supplementation help?
Knowledge-focused CompletedPatients will undergo at baseline and regular intervals: * clinically indicated bloodwork/urine and echocardiogram testing * biomarker studies Upon enrolment in the study patients will be divided into 4 groups normal, mildly deficient and severely deficient. Normal and mild vit…
Phase: PHASE4 • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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French ICUs treat more sick patients, but deaths drop
Knowledge-focused CompletedUsing data from the French National Uniform Hospital Discharge Database (systematically collecting administrative and medical information related to all hospitalized patients in France for care reimbursement purposes), the present study retrospectively assesses the activity of th…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC