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127005 trials found · Page 4889 of 6351
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New study tracks birth defect risks in MS drug BRIUMVI during pregnancy
Knowledge-focused Recruiting nowThe primary objective of the study is to compare the prevalence rate of major congenital malformations (MCM) between 2 cohorts of pregnant participants with MS who are exposed to BRIUMVI® and who are unexposed to BRIUMVI®.
Sponsor: TG Therapeutics, Inc. • Aim: Knowledge-focused
Last updated Aug 23, 2026 00:00 UTC
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Snap and speak: new study tests voice and face screening for allergies
Diagnosis CompletedCollect facial images and voice and audio of patients with rhinitis in the department of otolaryngology, and collect the examination results of patients with rhinitis who have received electronic fiber nasopharyngoscopy. Skin prick test to a standard panel of aeroallergens or by …
Sponsor: Zheng Liu • Aim: Diagnosis
Last updated Jun 26, 2026 18:41 UTC
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Can a team charter help catch depression in kids sooner?
Knowledge-focused OngoingPediatric depression is a global concern that has fueled efforts for enhanced detection and treatment engagement. While many health systems have implemented components of depression screening protocols, there is limited evidence of effective follow-up for pediatric depression. Ke…
Sponsor: University of California, San Diego • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Video instructions may boost colonoscopy success
Knowledge-focused Recruiting nowColonoscopy is a routine procedure for evaluating gastrointestinal symptoms, detecting colorectal cancer, and removing polyps. Its effectiveness depends on patient compliance with bowel preparation instructions. However, inadequate bowel preparation occurs in 20-25% of colonoscop…
Sponsor: Eskisehir Osmangazi University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Brain injury study seeks better recovery predictions
Knowledge-focused CompletedAcute subdural hematoma (ASDH) is the most common intracranial traumatic lesion that requires surgical intervention. Although there is extensive published research on acute subdural, there remains uncertainty regarding mortality risk and functional outcomes for patients. This stu…
Sponsor: Charles University, Czech Republic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Your phone as a doctor? new study tests app for vital signs
Knowledge-focused Recruiting nowThe purpose of the study is to verify and validate the parameters collected from mobile devices via the app named "Comestai" and from reference devices. The assessments considered to define comorbidities are included.. Specifically, collection of vital parameters (Blood Pressure,…
Sponsor: Buzzi Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Gum surgery recovery: spray or laser – which heals faster?
Symptom relief CompletedGingival enlargement may impair oral hygiene, esthetics, and periodontal health, and gingivectomy is commonly performed when non-surgical treatment is insufficient. Because gingivectomy wounds heal by secondary intention, postoperative wound healing and pain control are clinicall…
Sponsor: Akdeniz University • Aim: Symptom relief
Last updated Jun 27, 2026 13:06 UTC
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Hospital hands out gun locks to visitors in bid to stop shootings
Prevention CompletedThis study aims to enhance workplace safety by implementing a firearm safety program at Penn Medicine Pennsylvania Hospital (PAH). The option to store firearms securely during visits is offered to firearm owners. The study focuses on understanding barriers and facilitators to thi…
Sponsor: University of Pennsylvania • Aim: Prevention
Last updated Jun 27, 2026 08:04 UTC
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Which scan best spots C-Section scar defects? new study compares ultrasound, saline sonography, and MRI
Knowledge-focused CompletedUterine niche is a defect formed by poor healing of the lower uterine myometrium after cesarean section, defined as a depression of at least 2mm in the uterine myometrium at the cesarean scar; it is associated with gynecological symptoms and even life-threatening pregnancy compli…
Sponsor: International Peace Maternity and Child Health Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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Digital smile makeover: new trial uses face scans to guide Full-Mouth rehab
Disease control Recruiting nowParticipants with bite difficulties, smile dissatisfaction, and missing mandibular molars was rehabilitated using a fully digital, facially driven workflow. Integration of intraoral, facial, and CBCT data guided esthetic design, occlusion, and implant planning, resulting in preci…
Sponsor: Menoufia University • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Scientists track hidden gut disease in 450 asymptomatic patients
Knowledge-focused Recruiting nowThe purpose of this study is to evaluate disease progression, in terms of development of symptomatic disease and complications associated with IBD (e.g. fistula, abscess, stricture).
Sponsor: Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Glaucoma device Follow-Up study ends early
Disease control Stopped earlyThe purpose of this study is to evaluate long term safety and effectiveness of the STREAMLINE® SURGICAL SYSTEM
Sponsor: New World Medical, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Breast cancer survivors' arm capacity under the microscope
Knowledge-focused CompletedBreast cancer is the most common type of cancer among women worldwide. The incidence rate has reached approximately 16%. According to 2016 data from the Ministry of Health, the incidence of breast cancer in Turkey is 46.8 per 100,000 people and approximately 17,000 women are diag…
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Microneedling boosts gum surgery results in thin gums, small study finds
Disease control CompletedGingival Recession (GR) is a common finding among adults, regardless of the oral hygiene levels. When it is associated with esthetic impairment, dentin hypersensitivity, root caries, surgical treatment is indicated. Mid-buccal Gingival Recessions are an extremely prevalent condit…
Sponsor: Postgraduate Institute of Dental Sciences Rohtak • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Acupuncture vs. painkillers: new study for Post-Surgery knee relief
Symptom relief OngoingThis study is a concurrent non-randomized controlled pilot trial. We plan to recruit 80 patients following patellar dislocation surgery from Peking University Third Hospital in China, with at least 40 participants in each group. The study aims to evaluate the safety and efficacy …
Sponsor: Peking University Third Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Hospital help: does a drug coordinator cut risky pill use?
Knowledge-focused CompletedTo examine the effect of a Medication Coordinator, who facilitates medication reviews in close collaboration with patients using My Medication Plan to reduce the risk of post-hospital inappropriate medication usage.
Sponsor: University of Southern Denmark • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Lavender scent tested to ease Women's pain and anxiety during procedure
Symptom relief Stopped earlyOffice hysteroscopy is an invaluable practice to treat a myriad of gynecological processes. However, a limiting factor is the perceived pain and anxiety. In a randomized pilot study, treatment with lavender aromatherapy will significantly decrease the stress/anxiety levels associ…
Phase 2 • Sponsor: University of Florida • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
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Breathing patterns may skew Fluid-Readiness test in ICU shock patients
Knowledge-focused CompletedThis study explored how inspiratory effort affects the accuracy of the distensibility index of inferior vena cava (dIVC) in assessing fluid responsiveness (FR).This prospective observational study was conducted in an intensive care unit of a university hospital and included shock…
Sponsor: Jingyuan,Xu • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:08 UTC
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Which corneal transplant is best? 1,000-Patient study aims to find out
Knowledge-focused Recruiting nowOver the past decade, the management of Fuchs' endothelial corneal dystrophy (FECD) and pseudophakic bullous keratopathy (PBK) has been revolutionized by the development of posterior lamellar keratoplasty techniques: DSAEK and DMEK. DSAEK (Descemet Stripping Automated Endothelia…
Sponsor: Centre Hospitalier Régional Metz-Thionville • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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10-Year study tracks safety of new silicone breast implants
Knowledge-focused Recruiting nowPatients can undergo breast implant surgery for multiple reasons; cosmetic and reconstructive being the primary indications. In order to confidently state safety and due to strict regulation on medical devices it is important to maintain a record of safety and performance with al…
Sponsor: GCA (Eurosilicone) • Aim: Knowledge-focused
Last updated Jul 01, 2026 00:00 UTC