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127005 trials found · Page 4346 of 6351
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New MRI scan could spot stiff hearts without needles
Diagnosis Recruiting nowThis is a prospective case control study to determine the feasibility and utility of myocardial stiffness assessment by cardiac magnetic resonance elastography (MRE) in patients with cardiac amyloidosis.
Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated Jun 27, 2026 08:07 UTC
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Psoriasis patients' response to multiple biologics under scrutiny
Knowledge-focused Recruiting nowPsoriasis is a common skin condition that leads to patches of scaled skin which can be inflamed, sore and itchy. It can affect any area of skin on the body, as well as nails, and can be widespread and severe. Over the past 20 years, many new treatments have been developed and app…
Sponsor: Royal United Hospitals Bath NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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CBD tested as shield against Chemo's nerve pain
Prevention Recruiting nowThis is a pilot, prospective, randomized study evaluating the feasibility and acceptability of incorporating hemp-derived cannabidiol (CBD) supplementation to prevent oxaliplatin-induced peripheral neuropathy (OIPN) in patients receiving oxaliplatin-based chemotherapy for colorec…
Early phase 1 • Sponsor: Fox Chase Cancer Center • Aim: Prevention
Last updated Jun 27, 2026 07:55 UTC
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Robot freezes eggs as well as human hands?
Knowledge-focused Recruiting nowPurpose: This study aims to test whether a new automated system can freeze human eggs and embryos as effectively as the current manual method performed by laboratory staff. Background: Currently, freezing eggs and embryos during fertility treatments (IVF/ICSI) is done entirely b…
Sponsor: Conceivable Life Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Hands-On healing: can OMT give pitchers the edge?
Knowledge-focused By invitation onlyTo investigate the impact of manual medicine on key aspects of the kinetic chain on measures of performance in baseball players.
Sponsor: William Carey University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Heart rhythm study to track Long-Term outcomes in VT patients
Knowledge-focused Recruiting nowStructural heart disease-related ventricular tachycardia (SHD-VT) is associated with substantial morbidity and mortality. Although catheter ablation, ICD therapy, antiarrhythmic drugs, and other treatment strategies are widely used, real-world evidence regarding patient character…
Sponsor: Beijing Anzhen Hospital • Aim: Knowledge-focused
Last updated Jul 31, 2026 00:00 UTC
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Can writing away pain work? new study tests Self-Guided program for chronic sufferers
Symptom relief Recruiting nowThe investigators aim to conduct an open pilot trial to determine the initial feasibility of a self-directed writing-based intervention in individuals with chronic musculoskeletal pain and elevated pain catastrophizing. The investigators will assess the feasibility of recruitment…
Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Aug 23, 2026 00:00 UTC
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Stenting sooner may ease swallowing woes for esophageal stricture patients
Symptom relief Recruiting nowThis project is being done to compare two current treatment clinical options for management of RBES: 1) Frequent dilations followed by temporary esophageal stent placement if dilations fail, or 2) Early stent placement followed by dilations
Sponsor: Medical College of Wisconsin • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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New device aims to smooth wrinkles safely in all skin tones
Symptom relief Recruiting nowThe main purpose of the study is to collect information about how the device functions in a variety of treatment areas and skin types and to find out what changes, if any, occur in the skin treated with the study device compared to the skin that wasn't treated including patients …
Sponsor: Cytrellis Biosystems, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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Battery toothbrush beats manual in gum health showdown
Disease control CompletedA clinical research study design to compare the effectiveness of a battery toothbrush and dentifrice in reducing gingivitis and dental plaque in adults.
Phase 3 • Sponsor: Colgate Palmolive • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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Online classes before birth may shield new moms from PTSD
Symptom relief OngoingThe goal of this randomized controlled trial is determine if education on common events in labor in nulliparous women can reduce the postpartum traumatic symptoms. The main question it aims to answer are: * Does prenatal education on labor events reduce post-traumatic symptoms, …
Sponsor: University of California, San Diego • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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Cortisone or saline? new study aims to find best shot for wrist pain
Symptom relief Recruiting nowThe subject of the study is to use current treatment methods in patients with nerve compression in the wrist and compare their effects. The purpose of the study is to determine the most appropriate method by comparing the benefits of cortisone and serum injection in addition to e…
Sponsor: Kirsehir Ahi Evran Universitesi • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Zapping cartilage with radio waves could reshape noses without extra cuts
Symptom relief Recruiting nowThe goal of this study is to evaluate the efficacy of using the Vivaer low-temperature radio-frequency (LTRF) device to reshape ex-vivo human nasal or auricular cartilage for use in cosmetic and functional septorhinoplasty. The investigators hope to answer the following questions…
Sponsor: Indiana University • Aim: Symptom relief
Last updated Jun 27, 2026 08:00 UTC
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New home pregnancy test put to the test: will it be easy and accurate?
Diagnosis CompletedThis study is evaluating the ADEXUSDx® hCG CLIA moderately complex, FDA-cleared test for potential over the counter (OTC) use and marketing as the First To Know® (FTK) Pregnancy test. The investigational FTK Pregnancy test will be used to assess its clinical performance in the in…
Sponsor: NOWDiagnostics, Inc. • Aim: Diagnosis
Last updated Sep 10, 2026 00:00 UTC
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New group program aims to ease stress for special needs families
Symptom relief Recruiting nowParenting children with special health care needs can be stressful and weigh on the caregivers' mental health. For the individuals with special needs, the mismatch between their needs and the normative practice in the world around them can be frustrating and detrimental to their …
Sponsor: The University of Hong Kong • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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New study aims to boost cholesterol treatment in heart disease patients
Disease control By invitation onlyThe goal of this project is to study different approaches to improve the utilization of guideline directed medicines to lower cholesterol in patients with or at high risk of atherosclerosis (cholesterol buildup in the arteries).
Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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New combo therapy eases back pain without drugs?
Symptom relief CompletedThe study was conducted to determine the effects of Kaltenborn mobilization with and without proprioceptive neuromuscular facilitation technique on pain, range of motion and function in patients with chronic non-specific low back pain.
Sponsor: Riphah International University • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Mild depression after heart attack: a hidden risk?
Knowledge-focused Recruiting nowThis is an exploratory, prospective, non-profit study (SUBDIMA) designed to investigate the prevalence and potential prognostic significance of subclinical depression in patients admitted with a first acute myocardial infarction (AMI). Subclinical depression refers to the presenc…
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Sep 06, 2026 00:00 UTC
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Brain pressure may fuel heart rhythm problems in heart failure patients
Knowledge-focused CompletedThis study was designed to investigate predictors of atrial fibrillation (AF) in patients with heart failure with preserved ejection fraction (HFpEF), with a particular focus on the potential relationship between venous congestion and intracranial pressure dynamics. Among HFpEF p…
Sponsor: Ankara Ataturk Sanatorium Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Hormone therapy may reshape brain function, new study shows
Knowledge-focused Recruiting nowThe purpose of this study is to test whether and how a person's brain changes in the first few months after starting gender affirming hormone therapy (GAHT). The investigators want to know if GAHT changes: 1) cerebral blood flow (CBF), 2) brain structure, connectivity, and cognit…
Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC