Stroke treatment window could expand to 72 hours in new trial

NCT ID NCT06954155

First seen Nov 19, 2025

Summary

This study tests whether the clot-busting drug tenecteplase can help people who have had a stroke 24 to 72 hours earlier. Currently, such drugs are only given within a few hours. The trial will compare tenecteplase to standard care (blood thinners) in 330 adults with blocked brain arteries. The goal is to see if more patients can live independently at 90 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing tiantan hospital

    RECRUITING

    Beijing, 100070, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Tenecteplase (a clot-busting drug given as a single injection)

What this could lead to

If it works, this could extend the time window for treating strokes from hours to days, helping more people recover with less disability.

What could go wrong

This is an early phase 3 trial with only 330 participants. The drug may not improve outcomes and carries a risk of bleeding in the brain.

Conditions

The condition(s) this trial relates to.

ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.