Can a common muscle relaxant unlock better stroke rehab?
NCT ID NCT06666673
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This study tests how Tizanidine, a drug used for muscle stiffness, changes arm movement in people who have had a stroke. Researchers will measure brain activity, muscle responses, and movement patterns in 64 participants. The goal is to understand what limits movement after stroke, which could lead to better rehabilitation techniques.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Northwestern University, Dept. of PTHMS 645 N Michigan Ave, Suite 1100
RECRUITINGChicago, Illinois, 60611, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Tizanidine (Zanaflex)
What this could lead to
If successful, this study could point toward better rehabilitation methods for arm movement after stroke.
What could go wrong
This is a very early, small study (64 people) focused on understanding brain mechanisms, not on proving a new treatment. Tizanidine is already approved for spasticity, but its effects on voluntary movement are unclear.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.