Can a blood pressure cuff on your arm help your brain heal after a stroke?

NCT ID NCT06559241

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This study tests whether a noninvasive arm cuff therapy, called remote ischemic conditioning, can improve recovery in people who have had a major stroke and undergone a clot-removal procedure. The therapy involves briefly inflating and deflating a cuff on the upper arm to protect the brain from further damage. About 2105 participants will receive the therapy for either 14 or 30 days, and their functional outcomes will be measured at 90 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aerospace Central Hospital

    RECRUITING

    Beijing, 100049, China

    Contact

  • Anshan Changda Hospital

    RECRUITING

    Anshan, Liaoning, Anshan, China

    Contact

  • Army Medical University Noncommissioned Officer School Affiliated Hospital

    RECRUITING

    Shijiazhuang, Hebei, 050047, China

    Contact

  • Beijing Chao-Yang Hospital

    RECRUITING

    Beijing, 100020, China

    Contact

  • Beijing Daxing District People's Hospital

    RECRUITING

    Beijing, 102600, China

    Contact

  • Beijing Fangshan District First Hospital

    RECRUITING

    Beijing, Beijing Municipality, 100010, China

    Contact

  • Beijing Fengtai You'anmen Hospital

    RECRUITING

    Beijing, 100071, China

    Contact

  • Beijing Luhe Hospital affiliated to Capital Medical University

    RECRUITING

    Beijing, Beijing Municipality, 100000, China

    Contact

  • Beijing Red Cross Emergency Medical Center

    RECRUITING

    Beijing, 100085, China

    Contact

  • Cangzhou Central Hospital

    RECRUITING

    Cangzhou, Hebei, 061000, China

    Contact

  • Chongqing University Fuling Hospital

    NOT_YET_RECRUITING

    Chongqing, 408000, China

    Contact

  • Dalian Central Hospital

    NOT_YET_RECRUITING

    Dalian, Liaoning, 116000, China

  • Feixian People's Hospital

    SUSPENDED

    Linyi, Shandong, 273400, China

  • First People's Hospital of Tianmen

    SUSPENDED

    Tianmen, Hubei, 430000, China

  • Fujian Provincial Hospital

    NOT_YET_RECRUITING

    Fuzhou, Fujian, 350028, China

    Contact

  • Hebei General Hospital

    NOT_YET_RECRUITING

    Shijiazhuang, Hebei, 455001, China

    Contact

  • Henan Province People's Hospital

    NOT_YET_RECRUITING

    Zhengzhou, Henan, 450000, China

    Contact

  • Huanggang Central hospital

    RECRUITING

    Huanggang, Hubei, 438000, China

    Contact

  • Huangshi central hospital

    RECRUITING

    Huangshi, Hubei, 435000, China

    Contact

  • Inner Mongolia Autonomous Region People's Hospital

    NOT_YET_RECRUITING

    Hohhot, Inner Mongolia, 010000, China

    Contact

  • Jiaozuo Coal Industry Group Co., Ltd. Central Hospital

    RECRUITING

    Jiaozuo, Henan, 454000, China

    Contact

  • Jinan Third People's Hospital

    RECRUITING

    Jinan, Shandong, 250000, China

    Contact

  • Jingmen Central hospital

    RECRUITING

    Jingmen, Hubei, 448000, China

    Contact

  • Jingmen People's Hospital

    RECRUITING

    Jingmen, Hubei, 448000, China

    Contact

  • Liaocheng People's Hospital

    RECRUITING

    Liaocheng, Shandong, 252000, China

    Contact

  • Liaocheng Third People's Hospital

    RECRUITING

    Liaocheng, Shandong, 252000, China

    Contact

  • Luoyang Yanshi People's Hospital

    RECRUITING

    Luoyang, Henan, 471000, China

    Contact

  • Mianyang third people's hospital

    RECRUITING

    Mianyang, Sichuan, 621000, China

    Contact

  • Nanyang Central Hospital

    RECRUITING

    Nanyang, Henan, 473000, China

    Contact

  • Shengli Oilfield Central Hospital

    RECRUITING

    Dongying, Shandong, 257000, China

    Contact

  • Shenzhen Second People's Hospital

    NOT_YET_RECRUITING

    Shenzhen, Guangdong, 518000, China

    Contact

  • South China Hospital Affiliated to Shenzhen University

    RECRUITING

    Shenzhen, Guangdong, 518000, China

    Contact

  • Suzhou Municipal Hospital of Anhui Province

    RECRUITING

    Suzhou, Anhui, 234000, China

    Contact

  • Taihe County People's Hospital

    RECRUITING

    Taihe Chengguanzhen, Anhui, 236600, China

    Contact

  • The Central Hospital of Xiangtan

    NOT_YET_RECRUITING

    Xiangtan, Hunan, 411100, China

    Contact

  • The First Affiliated Hospital of Dalian Medical University

    RECRUITING

    Dalian, Liaoning, 116000, China

    Contact

  • The First Affiliated Hospital of Soochow University

    RECRUITING

    Suzhou, Jiangsu, 215006, China

    Contact

  • The Fourth Affiliated Hospital of Soochow University

    RECRUITING

    Suzhou, Jiangsu, 215000, China

    Contact

  • The Hongda Hospital of Jiamusi University

    RECRUITING

    Jiamusi, Heilongjiang, 154000, China

    Contact

  • The People's Hospital of Gaotang

    RECRUITING

    Liaocheng, Shandong, 252800, China

    Contact

  • The Second Affiliated Hospital of Wenzhou Medical University

    RECRUITING

    Wenzhou, Zhejiang, 325000, China

    Contact

  • The Second Nanning People's Hospital

    RECRUITING

    Nanning, Guangxi, 530000, China

    Contact

  • The Third People's Hospital of Hubei Province

    NOT_YET_RECRUITING

    Wuhan, Hubei, 430033, China

    Contact

  • The Third Xiangya Hospital of Central South University

    RECRUITING

    Changsha, Hunan, 410000, China

    Contact

  • Tongling People's Hospital

    RECRUITING

    Tongling, Anhui, China

    Contact

  • Xihua county people's hospital

    RECRUITING

    Zhoukou, Henan, 466600, China

    Contact

  • Xuanwu Hospital, Capital Medical University

    RECRUITING

    Beijing, 100053, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xunxian People's Hospital

    RECRUITING

    Hebi, Henan, 456250, China

    Contact

  • Ya 'an People's Hospital

    RECRUITING

    Ya'an, Sichuan, 625000, China

    Contact

  • Yeda Hospital

    RECRUITING

    Yantai, Shandong, China

    Contact

  • Yichang Central People's Hospital

    RECRUITING

    Yichang, Hubei, 443000, China

    Contact

  • Yueqing People's Hospital

    RECRUITING

    Yueqing, Zhejiang, 325600, China

    Contact

  • Zhangzhou Municipal Hospital of Fujian Province

    RECRUITING

    Zhangzhou, Fujian, 363000, China

    Contact

  • Zhongnan Hospital of Wuhan University

    RECRUITING

    Wuhan, Hubei, 430000, China

    Contact Phone: •••-•••-••••

  • the First People's Hospital of Changde

    RECRUITING

    Changde, Hunan, 415000, China

    Contact

  • the First People's Hospital of Chenzhou

    NOT_YET_RECRUITING

    Chenzhou, Hunan, 423000, China

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

remote ischemic conditioning (arm cuff device)

What this could lead to

If it works, this simple, noninvasive therapy could significantly improve functional recovery and reduce disability after a major stroke.

What could go wrong

This is a large Phase 3 trial, but earlier studies were small. The therapy may not provide meaningful benefit over standard care, and results may not apply to all stroke types.

Conditions

The condition(s) this trial relates to.

brain infarction ischemic stroke large artery stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.