New X-Ray technique could help rectal cancer patients avoid colostomy
NCT ID NCT06402864
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tests whether adding contact X-ray brachytherapy (a precise, high-dose radiation) to standard chemotherapy and radiation can help people with intermediate-stage rectal cancer keep their rectum instead of needing surgery to remove it. The study will enroll 212 adults whose tumors are 3.1 to 6 cm and have not spread. The goal is to see if more patients can avoid a permanent colostomy and live without the cancer coming back.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU de Saint Etienne
RECRUITINGSaint-Etienne, France, 42270, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre Antoine Lacassagne
RECRUITINGNice, France, 06189, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre Léon Bérard
RECRUITINGLyon, France, 69008, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre d'oncologie et de radiothérapie
RECRUITINGMâcon, France, 7100, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre de Haute Energie
RECRUITINGNice, France, 06000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre de radiotéhrapie Charcot
RECRUITINGLyon, France, 69110, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Européen
RECRUITINGMarseille, France, 13003, France
Contact Email: •••••@•••••
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Institut Gustave Roussy
RECRUITINGVillejuif, France, 94805, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Institut Sainte Catherine
RECRUITINGAvignon, France, 84918, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Institut de cancérologie de l'Ouest
RECRUITINGSaint-Herblain, France, 44800, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Orlam-Bayard
RECRUITINGVilleurbanne, France, 69100, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
contact X-ray brachytherapy (CXB)
What this could lead to
If successful, this could allow many patients with intermediate rectal cancer to avoid removal of the rectum and a permanent colostomy, preserving normal bowel function.
What could go wrong
This is a phase 3 trial, but results are not yet known. The added radiation may cause more side effects, and some patients may still need surgery or a stoma.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.