Magic mushroom study: does the 'Trip' cause the benefits?

NCT ID NCT06768944

First seen Jan 08, 2026 · Last updated May 27, 2026 · Updated 20 times

Summary

This study looks at whether the intense, mind-altering experience caused by psilocybin (the active ingredient in magic mushrooms) is necessary for its positive after-effects. Healthy volunteers will receive psilocybin along with either a placebo or risperidone, a drug that blocks the psychedelic effects. Researchers will then compare changes in mood, stress, and outlook to see if blocking the experience also blocks the benefits.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Calgary

    RECRUITING

    Calgary, Alberta, T2N 4N1, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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