Brain scans and blood tests may predict ECT success in severe depression
NCT ID NCT05630469
First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 32 times
Summary
This study is looking for ways to predict which patients with severe depression will respond well to electroconvulsive therapy (ECT). Researchers will use brain scans, blood tests, and spinal fluid samples from 30 patients before and after ECT. The goal is to find biological markers that can tell doctors ahead of time who is likely to benefit, helping personalize treatment decisions.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Department of Psychiatry and Psychotherapy, Medical University of Vienna
RECRUITINGVienna, 1090, Austria
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
electroconvulsive therapy (ECT)
What this could lead to
If successful, this could help doctors identify which patients with severe depression are most likely to benefit from ECT, making treatment more personalized.
What could go wrong
This is a small, early-stage study (30 people) focused on finding markers, not testing a new treatment. The results may not apply to all patients, and no immediate treatment benefit is guaranteed.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.