New hope for AML patients: targeted drug may keep cancer away after transplant

NCT ID NCT07463651

First seen Mar 17, 2026 · Last updated Jun 15, 2026 · Updated 16 times

Summary

This study tests whether a newer drug, gilteritinib, is better than the standard drug sorafenib at preventing leukemia from coming back in people with a specific genetic mutation (FLT3-ITD) after a stem cell transplant. About 594 adults and teens aged 14-70 will be randomly assigned to take one of the two drugs for up to 2 years. The goal is to see which drug keeps the cancer in remission longer with fewer side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ruijin Hospital, Shanghai Jiaotong University School of Medicine

    RECRUITING

    Shanghai, Shanghai Municipality, 200025, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • the First Affiliated Hosptital of Soochow University

    RECRUITING

    Suzhou, Jiangsu, 215006, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

acute myeloid leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.