Can a sedative help heal broken ribs? new trial aims to find out
NCT ID NCT04928300
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two drugs, dexmedetomidine and ketamine, to see which one better helps diaphragm function and pain in people with three or more broken ribs who are not having surgery. Sixty adults will receive a low-dose infusion of one drug or a placebo for five days. The goal is to improve breathing and reduce pain, which could speed recovery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Assiut university hospital
RECRUITINGAsyut, Assuit, Assuit universi, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dexmedetomidine (a sedative) and ketamine (an anesthetic)
What this could lead to
If it works, this could point toward a better way to manage pain and improve breathing in people with multiple broken ribs, reducing complications.
What could go wrong
This is a small, early-stage trial with only 60 participants, so results may not apply to everyone. Both drugs have side effects like sedation or confusion.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.