Assiut University

This study compares two types of breathing support for adults with pneumonia who are having trouble breathing. One method is high-velocity nasal insufflation (HVNI) and the other is noninvasive ventilation (NIV). The main goal is to see which method better prevents the need for a…

This study tests whether a silver liquid (silver diamine fluoride) is better than standard fluoride varnish at reducing cavity-causing bacteria in children aged 3 to 8 with tooth decay. Each child gets both treatments on different sides of their mouth, and bacteria levels are che…

This study tests a modified version of a glaucoma surgery called trabeculectomy for people whose eye pressure remains high after earlier combined cataract and glaucoma procedures. The goal is to safely lower eye pressure and prevent further vision loss. About 20 adults who had th…

This study compares two types of breathing support for adults who develop respiratory failure within 48 hours after major surgery. One method uses a mask (noninvasive ventilation), and the other uses a high-speed nasal cannula. The goal is to see which method helps patients wean …

This study looks at whether adding the antibiotic azithromycin to usual treatment can shorten hospital stays for people with a sudden worsening of idiopathic pulmonary fibrosis (a type of lung scarring). About 1,000 adults with mild to moderate disease will be randomly assigned t…

This study compares two surgical methods for treating undescended testicles in children. The goal is to see which technique helps the testicle move down into the scrotum more effectively. About 58 children with undescended testicles will take part. The study measures how far the …

This study tests a new surgical technique to treat pelvic organ prolapse in women having a hysterectomy. The surgery uses the body's own ligaments to support the pelvic organs. Ten women with stage 1 or higher prolapse will be enrolled. The goal is to see if the prolapse stage im…

This study tests a surgery that uses a muscle from the buttock to help people with severe bowel incontinence who haven't gotten better with other treatments. Ten adults who have a damaged or missing anal sphincter will get the operation. The goal is to see if the surgery can impr…

This study tests whether giving tranexamic acid (TXA) during hip reconstruction surgery in children can reduce blood loss and the need for blood transfusions. About 400 children scheduled for hip surgery will be randomly assigned to receive TXA or a placebo. The goal is to see if…

This study is testing a surgery to repair partially torn anterior cruciate ligaments (ACL) in the knee. Researchers want to see how well the surgery works by measuring knee function scores after the operation. The study will include 30 people aged 15 to 50 with partial ACL tears,…

This study tests whether giving tranexamic acid early after a traumatic brain injury can reduce harmful inflammation. Researchers will enroll 60 adults with mild or moderate head injuries. The goal is to see if this drug can improve recovery by calming the body's inflammatory res…

This study tests whether a simpler MRI scan (bp-MRI) can accurately diagnose bladder cancer and determine if it has spread into the muscle, without needing a contrast dye injection. Researchers will compare the new method to the standard contrast MRI in 58 adults suspected of hav…

This study is testing a new ultrasound measurement called the Lung Sliding Index (LSI) to see if it can help doctors tell apart different lung diseases like COPD, pneumonia, and pneumothorax. About 700 adults with various lung conditions and healthy volunteers will get a lung ult…

This study tests a new surgical technique that combines two types of endoscopy (hysteroscopy and laparoscopy) to repair a uterine niche—a pocket in the C-section scar that can cause spotting after periods. About 30 women with this condition will receive the surgery. The goal is t…

This study looks at whether a rectus sheath block (a type of nerve block) can improve breathing and reduce pain after major upper abdominal surgery. Researchers will measure diaphragm movement and pain scores in 60 adults. The goal is to see if this technique helps patients recov…

This study looks at whether starting to walk right after pelvic fracture surgery helps people recover faster and with less pain, compared to waiting a few weeks. About 50 adults aged 18 to 55 who had pelvic surgery will be randomly assigned to either walk immediately or wait. The…

This study looks at whether a specific nerve block (erector spinae plane block) can help control pain after laparoscopic abdominal surgery. Researchers will measure how long it takes for patients to need extra pain medicine and how much morphine they use. The trial involves 50 ad…

This study tests whether behavioral therapy can help adults with chronic cough that persists despite standard treatments. Participants must have signs of laryngeal hyperresponsiveness, like coughing when talking or in cold air. The main goal is to improve cough-related quality of…

This study compares two minimally invasive procedures—semi-rigid and flexible ureteroscopy—for removing upper ureter stones smaller than 2 cm. Researchers will measure which method is more effective, safer, faster, and more cost-effective. The trial involves 100 adults with upper…

This study tests two types of breathing support—high-velocity nasal cannula and non-invasive ventilation—in 80 adults with Guillain-Barré syndrome who have serious breathing trouble. The goal is to see which method helps more patients recover without needing a breathing tube. Res…

This study tests whether inhaling a drug called tranexamic acid through a nebulizer can reduce bleeding during sinus surgery. The goal is to make the surgery easier for the surgeon and safer for the patient. The trial will include 90 adults aged 18-65 who are scheduled for sinus …

This study tests two low-dose medicines (dexmedetomidine and ketamine) in 60 adults with three or more broken ribs who are not having surgery. The goal is to see which drug better improves diaphragm function, reduces pain, and lowers inflammation. Participants receive one of the …

This study tests if a nerve block (TAP block) is as good as or better than epidural pain relief for people having major abdominal cancer surgery. 50 adults will be randomly assigned to one of the two methods. The goal is to see which approach reduces the need for extra morphine a…

This study compares two breathing treatments for people with bronchiectasis who are having a sudden worsening of symptoms. It will test whether a high flow nasal cannula works as well as non-invasive ventilation. The goal is to see which device patients tolerate better and whethe…

This study tests whether giving a numbing medicine (bupivacaine) as a mist before surgery can reduce pain and the need for extra pain relievers in children aged 1-7 having cleft palate repair. About 60 children will take part, and half will get the numbing mist while the other ha…

This study compares two ways to sedate children before cleft palate repair: a combination of two drugs (dexmedetomidine and ketamine) given through a nebulizer versus dexmedetomidine alone. The goal is to see which approach works better for calming the child before surgery and pr…

This study tests whether a pectoral nerve block or a paravertebral block is better at preventing chronic pain after mastectomy. About 90 women having mastectomy will be randomly assigned to one of the two blocks. The goal is to see which approach reduces long-term pain and improv…

This study tests a new open surgery technique called TREPP for fixing inguinal hernias. The goal is to see if it reduces long-term groin pain and hernia return. About 30 adults with a primary hernia will take part. The surgery uses a small cut through the belly wall to place mesh…

This study tests whether adding blood flow restriction (BFR) training to standard physical therapy helps teens with a painful, rigid type of flatfoot. About 40 adolescents will be randomly assigned to receive either standard therapy or standard therapy plus BFR. The goal is to se…

This study compares two types of nerve blocks (TTPB and PIFB) to see which provides better pain relief after open heart surgery. About 90 adults aged 40-60 having coronary artery bypass will be enrolled. The goal is to reduce pain and the need for extra painkillers in the first 2…

This study looks at why some samples from thyroid nodule biopsies are not good enough for diagnosis. About 160 people with thyroid nodules will have their biopsy samples checked right away to see if more samples are needed. The goal is to find factors that lead to poor samples, s…

This study looks at what happens when a temporary stoma (an opening for waste) is placed in the middle of the belly, right through the main surgical cut. It will track 30 people who need a temporary ileostomy or colostomy to see how often the stoma needs to be moved, and how ofte…

This study looks at whether ultrasound can detect nerve changes in people with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) earlier than standard tests. Researchers will compare ultrasound findings with nerve conduction studie…

This study is developing and testing a new tool called CLEAR to predict when people with severe COPD can safely stop using a breathing machine. Researchers will follow 400 adults in the ICU who are ready to try breathing on their own. The goal is to see if CLEAR can better predic…

This study is for 750 adults with non-cystic fibrosis bronchiectasis, a chronic lung condition. Researchers want to build a tool called BASE that uses simple tests to classify how severe the disease is and predict the risk of flare-ups over the next year. Participants receive sta…

This study is for adults with non-cystic fibrosis bronchiectasis, a lung condition that causes coughing and infections. Researchers will use a computer model to identify different types of the disease based on patient data. The goal is to better understand the disease, not to tes…

This study tests whether special MRI scans can predict if chemotherapy is working for muscle-invasive bladder cancer. About 39 participants will get three MRI scans before, during, and after treatment. The goal is to avoid unnecessary delays and side effects for those who don't r…

This study is for people with bronchiectasis (a lung condition) who also have heart problems. Researchers want to see if heart issues make their lung disease worse and lower their quality of life. They will measure a heart-related protein in the blood and ask participants about t…

This study looks at whether chemotherapy given before bladder cancer surgery changes how well an MRI can see the tumor. About 76 people with muscle-invasive bladder cancer will take part. Some will get chemo before surgery, others will go straight to surgery. Their MRI results wi…