10-Year study to reveal hidden heart and metabolic risks of hormone therapy

NCT ID NCT06291675

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 34 times

Summary

This study follows 50 transgender men and women who have been on gender-affirming hormone therapy for 2 years. Researchers will use MRI scans, blood tests, and questionnaires to track changes in heart function, fat in the heart, liver, and pancreas, insulin system, and mental health at 2, 5, and 10 years. The goal is to understand the long-term health effects of hormone therapy, which most studies have only looked at short-term.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chiari Stoffwechselambulanz, Medical University of Vienna

    RECRUITING

    Vienna, State of Vienna, 1090, Austria

    Contact Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

The condition(s) this trial relates to.

Gender Dysphoria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.