Blood test may reveal hidden cancer mutations in breast cancer patients
NCT ID NCT06417801
First seen Nov 01, 2025
Summary
This study is collecting blood samples from 170 people with metastatic breast cancer to look for ESR1 gene mutations, which can make cancer resistant to hormone therapy. Researchers will compare these blood-based results with standard tissue tests. The goal is to better understand how common these mutations are and when they appear, which could improve future monitoring and treatment strategies.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ensino E Terapia de Inovação Clínica Amo - Ética
NOT_YET_RECRUITINGSalvador, Estado de Bahia, 41.950-640, Brazil
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Fundação Antonio Prudente - A.C. Camargo Cancer Center
NOT_YET_RECRUITINGSão Paulo, 01.509-900, Brazil
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Instituto D'Or de Pesquisa E Ensino - São Paulo
NOT_YET_RECRUITINGSão Paulo, 01401-002, Brazil
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Irmandade Da Santa Casa de Misericórdia de Porto Alegre
NOT_YET_RECRUITINGPorto Alegre, Rio Grande do Sul, 90020-090, Brazil
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Research Site
RECRUITINGSão Paulo, 04513-020, Brazil
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Sociedade Beneficente Israelita Brasileira Hospital Albert Eisntein
NOT_YET_RECRUITINGSão Paulo, 05652-000, Brazil
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help doctors better understand when and why ESR1 mutations emerge, potentially guiding future treatment decisions.
What could go wrong
This is an observational study, not testing a new treatment. It may not directly improve patient outcomes, and results might not apply to all breast cancer types.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.