CBD oil put to the test against chronic migraines
NCT ID NCT03972124
First seen May 07, 2026 · Last updated Jun 23, 2026 · Updated 5 times
Summary
This study tests whether CBD oil (a non-psychoactive cannabis compound) can reduce the number of headache days in people with chronic migraine. About 72 adults with a long history of migraines will receive either a low dose of CBD, a higher dose, or a placebo for several months. The main goal is to see if CBD leads to fewer headache days compared to placebo.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHAMP Research (Calgary Headache Assessment & Management Program)
RECRUITINGCalgary, Alberta, T3M 1M4, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
CBD oil (cannabidiol, purified to less than 1% THC)
What this could lead to
If it works, this could provide a new, non-psychoactive option for preventing chronic migraine headaches.
What could go wrong
This is a small Phase 2 trial, so results are preliminary. CBD may not reduce headache days more than placebo, and side effects are possible.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.