Which breathing aid works best for Guillain-Barré? new trial aims to find out

NCT ID NCT06996509

First seen Jun 25, 2026 · Last updated Jun 25, 2026

Summary

This study tests two breathing support devices—high-velocity nasal cannula (HVNI) and non-invasive ventilation (NIV)—in 80 adults with Guillain-Barré syndrome who have serious breathing trouble. The goal is to see which device helps more patients avoid needing a breathing tube within 30 days. Researchers will also measure comfort, ICU and hospital stays, and survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Assuit Univeristy

    RECRUITING

    Asyut, Assuit, 71515, Egypt

    Contact Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

  • Faculty of Medicine - Assiut University Hospitals - Assiut University - Egypt

    RECRUITING

    Asyut, 71515, Egypt

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

High-Velocity Nasal Insufflation (HVNI) device and Non-Invasive Ventilation (NIV) device

What this could lead to

If one device works better, it could help more Guillain-Barré patients breathe without needing a breathing tube, reducing complications and hospital stays.

What could go wrong

This is a small, early-stage trial (80 patients) at one hospital, so results may not apply to everyone. Both devices are already used, so no major new risks, but individual responses vary.

Conditions

The condition(s) this trial relates to.

Guillain-Barre syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.