New pill aims to reverse liver scarring in fatty liver patients

NCT ID NCT07610837

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This study tests an experimental drug called AZD2389 in 104 adults with fatty liver disease and advanced liver scarring. The drug is a pill that blocks a protein linked to scar formation. Researchers will check if it safely reduces scarring over 24 weeks compared to a placebo.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    NOT_YET_RECRUITING

    Chandler, Arizona, 85224, United States

  • Research Site

    NOT_YET_RECRUITING

    Jupiter, Florida, 33458, United States

  • Research Site

    NOT_YET_RECRUITING

    Miami, Florida, 33122, United States

  • Research Site

    NOT_YET_RECRUITING

    Port Orange, Florida, 32127, United States

  • Research Site

    NOT_YET_RECRUITING

    Kansas City, Missouri, 64131, United States

  • Research Site

    NOT_YET_RECRUITING

    St Louis, Missouri, 63123, United States

  • Research Site

    NOT_YET_RECRUITING

    Las Vegas, Nevada, 89106, United States

  • Research Site

    RECRUITING

    Morehead City, North Carolina, 28557, United States

  • Research Site

    NOT_YET_RECRUITING

    Raleigh, North Carolina, 27607, United States

  • Research Site

    NOT_YET_RECRUITING

    Westlake, Ohio, 44145, United States

  • Research Site

    NOT_YET_RECRUITING

    Yukon, Oklahoma, 73099, United States

  • Research Site

    NOT_YET_RECRUITING

    Clarksville, Tennessee, 37040, United States

  • Research Site

    NOT_YET_RECRUITING

    Austin, Texas, 78757, United States

  • Research Site

    NOT_YET_RECRUITING

    Denison, Texas, 75020, United States

  • Research Site

    NOT_YET_RECRUITING

    Georgetown, Texas, 78626, United States

  • Research Site

    NOT_YET_RECRUITING

    Houston, Texas, 77004, United States

  • Research Site

    NOT_YET_RECRUITING

    Houston, Texas, 77079, United States

  • Research Site

    RECRUITING

    San Antonio, Texas, 78215, United States

  • Research Site

    NOT_YET_RECRUITING

    San Antonio, Texas, 78222, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AZD2389 (an oral drug that blocks a protein called FAP to reduce liver scarring)

What this could lead to

If it works, this could point toward a new treatment that slows or reverses liver scarring in people with fatty liver disease.

What could go wrong

This is an early Phase 2 trial with only 104 people, so results may not apply to everyone. The drug may not improve liver scarring or could cause side effects.

Conditions

The condition(s) this trial relates to.

Liver Cirrhosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.