Kids' drug dosing mystery: new study aims to crack the code

NCT ID NCT03427736

First seen Jun 25, 2026 · Last updated Jun 25, 2026

Summary

This study tracks how common pain and anesthesia drugs behave in the bodies of children and teens aged 0 to 18. Researchers will measure drug levels in up to 500 participants who are already receiving these medications as part of their standard care. The goal is to create better dosing guidelines tailored to young patients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alfred I. DuPont Hospital for Children

    ACTIVE_NOT_RECRUITING

    Wilmington, Delaware, 19803, United States

  • Ann and Robert H. Lurie Childrens Hospital of Chicago

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Baylor College of Medicine

    WITHDRAWN

    Houston, Texas, 77030, United States

  • Cardinal Glennon Children's Hospital

    ACTIVE_NOT_RECRUITING

    St Louis, Missouri, 63104, United States

  • Children's Hospital Colorado

    TERMINATED

    Aurora, Colorado, 80045, United States

  • Dell Children's Medical Center of Texas

    WITHDRAWN

    Austin, Texas, 78723, United States

  • Duke University Medical Center

    RECRUITING

    Durham, North Carolina, 27701, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Sainte-Justine

    ACTIVE_NOT_RECRUITING

    Montreal, Quebec, T3T 1C5, Canada

  • Lucile Packard Children's Hospital

    ACTIVE_NOT_RECRUITING

    Stanford, California, 94305, United States

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oregon Health and Science University

    ACTIVE_NOT_RECRUITING

    Portland, Oregon, 97239, United States

  • The Hospital for Sick Children

    RECRUITING

    Toronto, Ontario, M5G 1X8, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Washington University School of Medicine

    ACTIVE_NOT_RECRUITING

    St Louis, Missouri, 63110, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ketorolac, Hydromorphone, Ketamine, Oxycodone, Morphine

What this could lead to

If successful, this could lead to safer, more effective dosing guidelines for pain and anesthesia drugs in children.

What could go wrong

This is an observational study, not a treatment trial. It only measures drug levels, so it won't directly improve care for participants.

Conditions

The condition(s) this trial relates to.

Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.