New asthma drug candidate AMG 691 begins first human safety tests

NCT ID NCT06637371

First seen Nov 01, 2025

Summary

This early-stage study tests the safety of a new drug called AMG 691 in healthy volunteers and people with mild-to-moderate asthma. The main goal is to see if the drug is safe and how the body processes it. Only 21 participants are enrolled, and the study is not yet recruiting. This is a first step to see if AMG 691 might help control asthma symptoms in the future.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ASTHMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Algemeen Ziekenhuis Sint Maarten-Emmaus vzw

    Mechelen, 2800, Belgium

  • Allergy Asthma and Clinical Research Center

    Oklahoma City, Oklahoma, 73120, United States

  • Brigham and Womens Hospital

    Boston, Massachusetts, 02115, United States

  • Chelsea and Westminster Hospital

    London, SW10 9NH, United Kingdom

  • Chesapeake Clinical Research Inc

    White Marsh, Maryland, 21162, United States

  • ClinCept, LLC

    Columbus, Georgia, 31904, United States

  • Clinical Medical and Analytical eXellence CMAX

    Adelaide, South Australia, 5000, Australia

  • Destiny Research Center

    Palmetto Bay, Florida, 33157, United States

  • Endeavor Clinical Trials

    San Antonio, Texas, 78240, United States

  • Mayflower Clinical

    South Dartmouth, Massachusetts, 02747, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Monroe Biomedical Research

    Monroe, North Carolina, 28112, United States

  • Monroe Biomedical Research

    North Charleston, South Carolina, 29406, United States

  • North Carolina Clinical Research

    Raleigh, North Carolina, 27607, United States

  • Orange County Research Center

    Lake Forest, California, 92630, United States

  • Prism Research LLC dba Nucleus Network

    Saint Paul, Minnesota, 55114, United States

  • The Medicines Evaluation Unit

    Manchester, M23 9QZ, United Kingdom

  • Translational Clinical Research LLC

    Aventura, Florida, 33180, United States

  • University of North Carolina Clinical and Translational Research Center

    Chapel Hill, North Carolina, 27599, United States

  • VPD Heart and Lung Research Institute

    Cambridge, CB2 0AY, United Kingdom

  • Winchester District Memorial Hospital

    Winchester, Ontario, K0C 2K0, Canada

Conditions

The condition(s) this trial relates to.

asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.