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Can zinc oxide soothe your canker sore pain?

NCT ID NCT07565181

Symptom relief Sponsor: Faculty of Dental Medicine for Girls Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested if zinc oxide ointment can help heal painful canker sores. One hundred people with canker sores used either the zinc ointment or a placebo three times a day for six days. Researchers measured pain and how the sores affected daily life to see if the ointment made a difference.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

100 people

The number who actually took part.

Started

Jun 2025

Finished

Mar 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 to 45 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * -Systemically healthy subjects suffering from minor oral RAS. * Patients of both sexes, aged 16-45 years (to avoid the potential effects of age on healing). * Participants had not received any treatment for the ulcers before being included in the study and had no active periodontitis. * Ulcers are of a duration of less than 48 hours. Exclusion Criteria: * -Participants with removable prosthetic or orthodontic appliances (to avoid potential effects on healing). * Tobacco chewers, smokers or alcoholics. * Pregnant or lactating females. * Patients who had previously or are presently taking medications that could affect events associated with the healing process (erg, corticosteroids, oral antidiabetics, non-steroidal anti-inflammatory drugs, immune-modulating agents).

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Conditions

The condition(s) this trial relates to.

aphthous stomatitis canker sore

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Recurrent aphthous stomatitis

Contacts and locations

Locations

  • Faculty of Dental Medicine for Girls ,Al-Azhar university

    Cairo, Cairo Governorate, 11651, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.