Ginger vs antibiotics: new study fights tooth infections in kids
NCT ID NCT07488416
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two pastes used to sterilize infections and repair tissue in baby molars that have died. One paste contains zinc oxide mixed with 6-gingerol (a compound from ginger), and the other is a standard triple antibiotic paste. Sixty children aged 4 to 8 with at least two infected baby molars will be treated and followed for pain and tooth mobility. The goal is to see if the ginger-based paste works as well as antibiotics, potentially offering a more natural option.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- zinc oxide/6-gingerol mix
- What this could lead to
- If it works, this could offer a natural alternative to antibiotics for treating infected baby teeth, reducing antibiotic use.
- What could go wrong
- This is a small early-stage trial with only 60 children, so results may not apply broadly. The ginger-based paste might be less effective than the standard antibiotic paste.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2024
- Expected to finish
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May 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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4 to 8 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age from 4 to 8 years. * Both sexes * Children must have at least two restorable non-vital primary molars * Periapical radiolucency. * Pain on mastication. * Pathological mobility. * Internal or external root resorption. * Furcation involvement should not extend to the developing tooth germ. Exclusion Criteria: * Presence of systemic diseases. * Teeth with physiological mobility near exfoliation time. * Teeth with vital pulp.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Al-Azhar University
RECRUITINGCairo, 11651, Egypt
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