Simple combo may stop painful Hand-Foot rash in cancer patients
NCT ID NCT06856590
First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 22 times
Summary
This study looked at whether taking zinc supplements and using a strong steroid cream (clobetasol) can prevent or lessen hand-foot skin reaction, a painful rash caused by the cancer drug regorafenib. About 150 adults with certain cancers starting regorafenib for the first time took part. They were split into three groups: zinc plus cream, cream alone, or zinc alone. The goal was to see which approach best reduces rash severity and improves quality of life.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Afyonkarahisar University of Health Sciences Hospital
Afyonkarahisar, 03030, Turkey (Türkiye)
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Ankara Etlik City Hospital
Ankara, Yenimahalle, 06170, Turkey (Türkiye)
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Ankara University Faculty of Medicine Hospital
Ankara, 06230, Turkey (Türkiye)
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Bursa Uludağ University Hospital
Bursa, Nilüfer, 16059, Turkey (Türkiye)
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Dicle University Hospital
Diyarbakır, 21280, Turkey (Türkiye)
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Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital
Ankara, Yenimahalle, 06200, Turkey (Türkiye)
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Gazi University
Ankara, Yenimahalle, 06500, Turkey (Türkiye)
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Hacettepe University Faculty of Medicine Hospital
Ankara, 06230, Turkey (Türkiye)
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Karadeniz Technical University Hospital
Trabzon, Ortahisar, 61080, Turkey (Türkiye)
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Necmettin Erbakan University Meram Faculty of Medicine Hospital
Konya, Meram, 42080, Turkey (Türkiye)
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Sakarya University Hospital
Sakarya, Serdivan, 54050, Turkey (Türkiye)
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Tekirdağ Namık Kemal University Hospital
Tekirdağ, 59100, Turkey (Türkiye)
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Van Yüzüncü Yıl University Dursun Odabaş Hospital
Van, 65080, Turkey (Türkiye)
Conditions
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