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Zika in pregnancy: major study tracks birth defects in french caribbean

NCT ID NCT02916732

First seen Dec 12, 2025 · Last updated Jun 19, 2026 · Updated 19 times

Summary

This completed study observed nearly 27,000 pregnant women in French Caribbean departments during the 2016 Zika epidemic. Researchers tracked Zika infections and their impact on pregnancy, including rates of microcephaly and other fetal abnormalities. The goal was to better understand the risks of Zika during pregnancy using routine medical data.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CH Andrée Rosemon (CHAR)

    Cayenne, French Guiana

  • CH de l'Ouest Guyanais Franck Joly (CHOG)

    Saint-Laurent-du-Maroni, French Guiana

  • CHU de Martinique

    Fort-de-France, Martinique

  • CHU de Pointe à Pitre/Les Abymes

    Pointe-à-Pitre, Guadeloupe

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could provide crucial data on how Zika infection during pregnancy affects fetal development, helping guide future prevention and care.

What could go wrong

This is an observational study, not a treatment trial, so it won't directly lead to a cure or therapy. Results may be limited by the specific population and epidemic context.

Conditions

The condition(s) this trial relates to.

Congenital Abnormalities microcephaly Zika virus infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.