New drug combo aims to tackle Hard-to-Treat leukemia
NCT ID NCT07355335
First seen Jan 22, 2026 · Last updated May 25, 2026 · Updated 20 times
Summary
This early-stage study tests two experimental drugs, ziftomenib and mezigdomide, given together to adolescents and adults with a specific type of acute myeloid leukemia (AML) that has come back or not responded to treatment. The main goal is to find a safe dose and check for side effects. About 24 people with either a KMT2A rearrangement or NPM1 mutation will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Contact
Conditions
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