New hope for advanced NETs: zanzalintinib takes on everolimus

NCT ID NCT06943755

Recruiting now Disease control Sponsor: Exelixis Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 33 times

Summary

This study compares a new drug, zanzalintinib, to the current standard everolimus in people with advanced neuroendocrine tumors that have already been treated. The goal is to see which drug better slows cancer growth. About 440 adults with pancreatic or other neuroendocrine tumors will take part.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Exelixis Clinical Site # 4
WITHDRAWN

San Juan, 00927, Puerto Rico
Exelixis Clinical Site #1
RECRUITING

Grand Rapids, Michigan, 49546, United States
Exelixis Clinical Site #10
RECRUITING

Dallas, Texas, 75264, United States
Exelixis Clinical Site #11
RECRUITING

Tampa, Florida, 33612, United States
Exelixis Clinical Site #12
RECRUITING

Santa Monica, California, 90404, United States
Exelixis Clinical Site #13
RECRUITING

Fairfax, Virginia, 22031, United States
Exelixis Clinical Site #14
RECRUITING

Albuquerque, New Mexico, 87131, United States
Exelixis Clinical Site #15
RECRUITING

Salt Lake City, Utah, 84112, United States
Exelixis Clinical Site #16
RECRUITING

Los Angeles, California, 90033, United States
Exelixis Clinical Site #17
RECRUITING

Chapel Hill, North Carolina, 27599, United States
Exelixis Clinical Site #18
RECRUITING

Beverly Hills, California, 90211, United States
Exelixis Clinical Site #19
RECRUITING

Washington D.C., District of Columbia, 20007, United States
Exelixis Clinical Site #2
RECRUITING

San Juan, 00909, Puerto Rico
Exelixis Clinical Site #20
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
Exelixis Clinical Site #21
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States
Exelixis Clinical Site #22
RECRUITING

London, England, SE5 9RS, United Kingdom
Exelixis Clinical Site #23
RECRUITING

Metairie, Louisiana, 70006, United States
Exelixis Clinical Site #24
RECRUITING

Knoxville, Tennessee, 37920, United States
Exelixis Clinical Site #25
RECRUITING

Omaha, Nebraska, 68198, United States
Exelixis Clinical Site #26
RECRUITING

Seoul, 06351, South Korea
Exelixis Clinical Site #27
RECRUITING

Portland, Oregon, 97210, United States
Exelixis Clinical Site #28
RECRUITING

Columbus, Ohio, 43221, United States
Exelixis Clinical Site #29
RECRUITING

Vallejo, California, 94589, United States
Exelixis Clinical Site #3
RECRUITING

Charlottesville, Virginia, 22903, United States
Exelixis Clinical Site #30
RECRUITING

Seoul, 02841, South Korea
Exelixis Clinical Site #31
RECRUITING

Milwaukee, Wisconsin, 53226, United States
Exelixis Clinical Site #32
RECRUITING

Seoul, 03722, South Korea
Exelixis Clinical Site #33
RECRUITING

Sheffield, S10 2SJ, United Kingdom
Exelixis Clinical Site #34
RECRUITING

Seattle, Washington, 98109, United States
Exelixis Clinical Site #35
RECRUITING

Jacksonville, Florida, 32224, United States
Exelixis Clinical Site #36
RECRUITING

Phoenix, Arizona, 85054, United States
Exelixis Clinical Site #37
RECRUITING

Warsaw, 53-673, Poland
Exelixis Clinical Site #38
RECRUITING

Rochester, Minnesota, 55905, United States
Exelixis Clinical Site #39
RECRUITING

Cleveland, Ohio, 44106, United States
Exelixis Clinical Site #40
RECRUITING

Saint Leonards, New South Wales, 2065, Australia
Exelixis Clinical Site #41
RECRUITING

Seoul, 05505, South Korea
Exelixis Clinical Site #42
RECRUITING

Tucson, Arizona, 85724, United States
Exelixis Clinical Site #43
RECRUITING

Birmingham, Alabama, 35294, United States
Exelixis Clinical Site #44
RECRUITING

Madrid, 28046, Spain
Exelixis Clinical Site #45
RECRUITING

Katowice, 40-514, Poland
Exelixis Clinical Site #46
RECRUITING

Seoul, 03080, South Korea
Exelixis Clinical Site #47
RECRUITING

Detroit, Michigan, 48202, United States
Exelixis Clinical Site #48
RECRUITING

Graz, 8036, Austria
Exelixis Clinical Site #49
RECRUITING

Toronto, M4N3M5, Canada
Exelixis Clinical Site #5
RECRUITING

St Louis, Missouri, 63110, United States
Exelixis Clinical Site #50
RECRUITING

Liverpool, L7 8YA, United Kingdom
Exelixis Clinical Site #51
RECRUITING

Clayton, Victoria, 3168, Australia
Exelixis Clinical Site #52
RECRUITING

Tübingen, 72076, Germany
Exelixis Clinical Site #53
RECRUITING

Rochester, New York, 14642, United States
Exelixis Clinical Site #54
RECRUITING

Palo Alto, California, 94305, United States
Exelixis Clinical Site #55
RECRUITING

Herston, 4029, Australia
Exelixis Clinical Site #56
RECRUITING

Madrid, 28034, Spain
Exelixis Clinical Site #57
RECRUITING

Fargo, North Dakota, 58102, United States
Exelixis Clinical Site #59
RECRUITING

Buffalo, New York, 14263, United States
Exelixis Clinical Site #6
RECRUITING

Durham, North Carolina, 27710, United States
Exelixis Clinical Site #60
RECRUITING

Santander, 39008, Spain
Exelixis Clinical Site #61
RECRUITING

Ottawa, K1H8L6, Canada
Exelixis Clinical Site #62
RECRUITING

Seville, 41013, Spain
Exelixis Clinical Site #63
RECRUITING

Hong Kong, China
Exelixis Clinical Site #64
RECRUITING

Valencia, 46026, Spain
Exelixis Clinical Site #65
RECRUITING

Nashville, Tennessee, 37232, United States
Exelixis Clinical Site #66
RECRUITING

Murcia, 30008, Spain
Exelixis Clinical Site #67
RECRUITING

Woodville South, South Australia, 5011, Australia
Exelixis Clinical Site #68
RECRUITING

Clayton, Victoria, 3168, Australia
Exelixis Clinical Site #69
RECRUITING

Warsaw, Masovian Voivodeship, 02-034, Poland
Exelixis Clinical Site #7
RECRUITING

New York, New York, 10029, United States
Exelixis Clinical Site #70
RECRUITING

Roma, 00185, Italy
Exelixis Clinical Site #71
RECRUITING

Oxford, England, OX3 7LE, United Kingdom
Exelixis Clinical Site #72
RECRUITING

Gliwice, Ślaskie, 44-102, Poland
Exelixis Clinical Site #73
RECRUITING

Madrid, 28041, Spain
Exelixis Clinical Site #74
RECRUITING

Santiago de Compostela, A Coruña, 15706, Spain
Exelixis Clinical Site #75
RECRUITING

Würzburg, 97080, Germany
Exelixis Clinical Site #76
RECRUITING

Barcelona, 08029, Spain
Exelixis Clinical Site #77
RECRUITING

China, Hong Kong
Exelixis Clinical Site #78
RECRUITING

Naples, Naples, 80131, Italy
Exelixis Clinical Site #79
RECRUITING

Zaragoza, 50009, Spain
Exelixis Clinical Site #8
RECRUITING

Boston, Massachusetts, 02215, United States
Exelixis Clinical Site #80
RECRUITING

Oviedo, Principality of Asturias, 33011, Spain
Exelixis Clinical Site #9
RECRUITING

Lexington, Kentucky, 40536, United States
Exelixis Clinical Site 58
RECRUITING

Berlin, 13125, Germany

Conditions

Explore the condition pages connected to this study.

EXTRA-PANCREATIC NEUROENDOCRINE TUMOR (EPNET) EXTRA-PANCREATIC NEUROENDOCRINE TUMOR (EPNET) PANCREATIC NEUROENDOCRINE TUMOR (PNET)